Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF2S2
  • Mouse genes Eif2s2
  • Rat genes Eif2s2
  • Zfish genes eif2s2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif2s2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P16333	Human	PMID:11959995
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05198	Human	PMID:16288713
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P41091	Human	PMID:16288713
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05198	Human	PMID:16932749
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P78344	Human	PMID:16932749
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P55010	Human	PMID:21745818
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:Q9Y6E2	Human	PMID:21745818
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:Q9Y6E2	Human	PMID:25147208
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05198	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P41091	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P01138	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P05412	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P20340-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P43681	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:Q92673	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF2S2	IPI	UniProtKB:Q99683	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Eif2s2	IPI	UniProtKB:P16333|UniProtKB:Q99M51	Mouse	MGI:MGI:5613483|PMID:11959995
Molecular Function	GO:0005515	protein binding	Eif2s2	IPI	UniProtKB:B2RZ33	Rat	PMID:11959995|RGD:10047282
Molecular Function	GO:0005515	protein binding	Eif2s2	IPI	RGD:620963|RGD:1561279	Rat	PMID:2450747|RGD:10395356
Molecular Function	GO:0003723	RNA binding	EIF2S2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF2S2	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF2S2	IDA		Human	PMID:16289705
Cellular Component	GO:0005737	cytoplasm	EIF2S2	IDA		Human	PMID:12426392
Cellular Component	GO:0005850	eukaryotic translation initiation factor 2 complex	EIF2S2	IDA		Human	PMID:23063529
Cellular Component	GO:0045202	synapse	Eif2s2	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif2s2	IDA		Mouse	PMID:25211037
Biological Process	GO:0001701	in utero embryonic development	Eif2s2	IMP	MGI:MGI:3838881	Mouse	PMID:19168544
Biological Process	GO:0002176	male germ cell proliferation	Eif2s2	IMP	MGI:MGI:3838881	Mouse	PMID:19168544
Biological Process	GO:0008584	male gonad development	Eif2s2	IMP	MGI:MGI:3838881	Mouse	PMID:19168544
Biological Process	GO:0006413	translational initiation	EIF2S2	IDA		Human	PMID:10563826

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern