Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EFNB1
  • Mouse genes Efnb1
  • Rat genes Efnb1
  • Zfish genes efnb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046875	ephrin receptor binding	EFNB1	IDA		Human	PMID:23711177
Molecular Function	GO:0046875	ephrin receptor binding	Efnb1	IPI	PR:Q03145	Mouse	PMID:14988728
Molecular Function	GO:0046875	ephrin receptor binding	Efnb1	IPI	PR:Q60610	Mouse	PMID:14988728
Molecular Function	GO:0005515	protein binding	EFNB1	IPI	UniProtKB:P04626	Human	PMID:22279592
Molecular Function	GO:0005515	protein binding	EFNB1	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNB1	IPI	UniProtKB:Q62083	Human	PMID:9883737
Molecular Function	GO:0005515	protein binding	Efnb1	IPI	UniProtKB:O08992	Mouse	MGI:MGI:5508301|PMID:9920925
Molecular Function	GO:0005515	protein binding	Efnb1	IPI	UniProtKB:P49769	Mouse	MGI:MGI:3619856|PMID:16511561
Molecular Function	GO:0005515	protein binding	Efnb1	IPI	PR:P52801	Mouse	PMID:14988728
Molecular Function	GO:0005515	protein binding	Efnb1	IPI	PR:Q8C0C0	Mouse	PMID:19515908
Molecular Function	GO:0005515	protein binding	Efnb1	IPI	UniProtKB:P54763	Rat	PMID:9883737|RGD:8554504
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	EFNB1	IDA		Human	PMID:23711177
Cellular Component	GO:0009986	cell surface	EFNB1	IDA		Human	PMID:12970314
Cellular Component	GO:0005737	cytoplasm	Efnb1	IDA		Mouse	PMID:19515908
Cellular Component	GO:0070062	extracellular exosome	EFNB1	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Efnb1	IDA		Rat	PMID:19915143|RGD:13702172
Cellular Component	GO:0098978	glutamatergic synapse	Efnb1	IMP		Rat	PMID:19915143|RGD:13702172
Cellular Component	GO:0045121	membrane raft	Efnb1	IDA		Mouse	PMID:10197531
Cellular Component	GO:0005634	nucleus	Efnb1	IDA		Mouse	PMID:19515908
Cellular Component	GO:0005886	plasma membrane	EFNB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0042734	presynaptic membrane	Efnb1	IDA		Rat	PMID:19915143|RGD:13702172
Cellular Component	GO:0045202	synapse	Efnb1	IDA		Rat	PMID:9883737|RGD:8554504
Biological Process	GO:0007411	axon guidance	Efnb1	IMP		Mouse	PMID:11731465
Biological Process	GO:1990402	embryonic liver development	efnb1	IMP	ZFIN:ZDB-GENO-170202-23	Zfish	PMID:27825440
Biological Process	GO:0009880	embryonic pattern specification	Efnb1	IMP	MGI:MGI:3039289	Mouse	PMID:15037550
Biological Process	GO:0007399	nervous system development	Efnb1	IMP		Rat	PMID:12139920|RGD:727396
Biological Process	GO:0001755	neural crest cell migration	Efnb1	IMP	MGI:MGI:3039290	Mouse	PMID:15037550
Biological Process	GO:0003404	optic vesicle morphogenesis	efnb1	IGI	ZFIN:ZDB-MRPHLNO-050523-1,ZFIN:ZDB-MRPHLNO-131219-1	Zfish	PMID:24026122
Biological Process	GO:0003404	optic vesicle morphogenesis	efnb1	IGI	ZFIN:ZDB-MRPHLNO-050522-1,ZFIN:ZDB-MRPHLNO-050523-1,ZFIN:ZDB-MRPHLNO-131219-1	Zfish	PMID:24026122
Biological Process	GO:0042102	positive regulation of T cell proliferation	Efnb1	IDA		Mouse	PMID:15502157
Biological Process	GO:0099054	presynapse assembly	Efnb1	IDA		Rat	PMID:19915143|RGD:13702172
Biological Process	GO:0099054	presynapse assembly	Efnb1	IMP		Rat	PMID:19915143|RGD:13702172
Biological Process	GO:2000785	regulation of autophagosome assembly	EFNB1	IDA		Human	PMID:33280498
Biological Process	GO:0031295	T cell costimulation	Efnb1	IDA		Mouse	PMID:15599401
Biological Process	GO:0042098	T cell proliferation	Efnb1	IDA		Mouse	PMID:15502157

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern