Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EDAR
  • Mouse genes Edar
  • Rat genes Edar
  • Zfish genes edar
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Edar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EDAR	IPI	UniProtKB:Q92838	Human	PMID:11039935
Molecular Function	GO:0005515	protein binding	EDAR	IPI	UniProtKB:Q92838-1	Human	PMID:27144394
Molecular Function	GO:0004888	transmembrane signaling receptor activity	EDAR	IDA		Human	PMID:11039935
Cellular Component	GO:0045177	apical part of cell	Edar	IDA		Mouse	PMID:12629675
Cellular Component	GO:0005886	plasma membrane	Edar	IDA		Mouse	PMID:12629675
Biological Process	GO:0060348	bone development	edar	IMP	ZFIN:ZDB-GENO-090324-6	Zfish	PMID:18833299
Biological Process	GO:0061972	dermal bone morphogenesis	edar	IMP	ZFIN:ZDB-GENO-180503-16	Zfish	PMID:28835471
Biological Process	GO:0007631	feeding behavior	edar	IMP	ZFIN:ZDB-GENO-220228-2	Zfish	PMID:32647268
Biological Process	GO:0007631	feeding behavior	edar	IMP	ZFIN:ZDB-GENO-220228-3	Zfish	PMID:32647268
Biological Process	GO:0033333	fin development	edar	IMP	ZFIN:ZDB-GENO-980202-795	Zfish	PMID:24173565
Biological Process	GO:0001942	hair follicle development	Edar	IMP	MGI:MGI:1856017	Mouse	PMID:544312
Biological Process	GO:0001942	hair follicle development	Edar	IGI	MGI:MGI:1931001	Mouse	PMID:544312
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Edar	IMP	MGI:MGI:1856017	Mouse	PMID:544312
Biological Process	GO:0043473	pigmentation	Edar	IMP	MGI:MGI:1856017	Mouse	PMID:544312
Biological Process	GO:0010628	positive regulation of gene expression	Edar	IDA		Mouse	PMID:18508042
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Edar	IDA		Mouse	PMID:12629675
Biological Process	GO:0060662	salivary gland cavitation	Edar	IDA		Mouse	PMID:12629675

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern