Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC2LI1
  • Mouse genes Dync2li1
  • Rat genes Dync2li1
  • Zfish genes dync2li1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync2li1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045504	dynein heavy chain binding	DYNC2LI1	IDA		Human	PMID:29742051
Molecular Function	GO:0045504	dynein heavy chain binding	Dync2li1	IPI	UniProtKB:Q9JJ79	Rat	PMID:12432068|RGD:10047254
Molecular Function	GO:0005515	protein binding	DYNC2LI1	IPI	UniProtKB:P00441	Human	PMID:21252941
Molecular Function	GO:0005515	protein binding	DYNC2LI1	IPI	UniProtKB:Q8NCM8	Human	PMID:29742051
Cellular Component	GO:0045177	apical part of cell	Dync2li1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0005930	axoneme	Dync2li1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0005813	centrosome	DYNC2LI1	IDA		Human	PMID:26130459
Cellular Component	GO:0036064	ciliary basal body	DYNC2LI1	IDA		Human	PMID:26130459
Cellular Component	GO:0035869	ciliary transition zone	DYNC2LI1	IDA		Human	PMID:26130459
Cellular Component	GO:0005929	cilium	dync2li1	IMP	ZFIN:ZDB-MRPHLNO-100216-1	Zfish	PMID:19474410|ZFIN:ZDB-PUB-090601-13
Cellular Component	GO:0005737	cytoplasm	DYNC2LI1	IDA		Human	PMID:26130459
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2LI1	IDA		Human	PMID:21723285
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2LI1	IDA		Human	PMID:31451806
Cellular Component	GO:0005829	cytosol	DYNC2LI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031514	motile cilium	Dync2li1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0097730	non-motile cilium	dync2li1	IMP	ZFIN:ZDB-MRPHLNO-100216-1	Zfish	PMID:19474410
Biological Process	GO:0060271	cilium assembly	Dync2li1	IMP	MGI:MGI:3505858	Mouse	PMID:15371312
Biological Process	GO:0007368	determination of left/right symmetry	Dync2li1	IMP	MGI:MGI:3505858	Mouse	PMID:15371312
Biological Process	GO:0042073	intraciliary transport	dync2li1	IMP	ZFIN:ZDB-MRPHLNO-100216-1	Zfish	PMID:19474410
Biological Process	GO:0035735	intraciliary transport involved in cilium assembly	DYNC2LI1	IMP		Human	PMID:26077881
Biological Process	GO:1902017	regulation of cilium assembly	DYNC2LI1	IMP		Human	PMID:26077881

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern