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Dync2li1
Gene Detail
 Symbol
Name
ID
Dync2li1
dynein cytoplasmic 2 light intermediate chain 1
MGI:1913996
Synonyms 4933404O11Rik, CGI-60, D2lic, LIC3, mD2LIC, MGC:40646, MGC:7211
Feature Type protein coding gene
Genetic Map
Chromosome 17
55.02 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:84626496-84655558 bp, + strand
From Ensembl annotation of GRCm38

  29063 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9336  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 1 zebrafish

Gene Tree: Dync2li1

Human
homologs
Human Homolog DYNC2LI1, dynein, cytoplasmic 2, light intermediate chain 1
NCBI Gene ID 51626
neXtProt AC  NX_Q8TCX1
Human Synonyms  D2LIC, LIC3
Human Chr (Location)  2p25.1-p24.1; chr2:43774039-43827616 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(5) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this allele die before embryonic day 11.5. They display neural tube defects in addition to a variety developmental patterning abnormalities.
 
Interactions
Dync2li1 interacts with 43 markers (Mir133a-1, Mir133a-2, Mir135a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell projection organization, cilium assembly, ...
Component apical part of cell, axoneme, ...
Function motor activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (7)    Tissues (7)    Images (3)
Theiler Stages: 10, 11, 13, 14, 15, 18
Assay TypeResults
RNA in situ 7
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) cDNA(30)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000024253 (Evidence)
Entrez Gene213575 (Evidence)
UniGene246119
DFCITC1580039, TC1632067
DoTSDT.40168827, DT.94173600
NIA Mouse Gene IndexU018288
Consensus CDS ProjectCCDS29000.1
International Mouse Knockout Project StatusDync2li1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024253 Ensembl Gene Model | MGI Sequence Detail 29063 C57BL/6J ±  kb
transcript ENSMUST00000025101 Ensembl | MGI Sequence Detail 1324 Not Applicable 
polypeptide ENSMUSP00000025101 Ensembl | MGI Sequence Detail 351 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(198 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022780 Dynein family light intermediate chain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000006776 cytoplasmic dynein 2 light intermediate chain 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory