Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC2I1
  • Mouse genes Dync2i1
  • Rat genes Dync2i1
  • Zfish genes dync2i1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync2i1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045503	dynein light chain binding	DYNC2I1	IPI	UniProtKB:Q8WW35	Human	PMID:25830415
Molecular Function	GO:0005515	protein binding	DYNC2I1	IPI	UniProtKB:Q9Y266	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	DYNC2I1	IPI	UniProtKB:Q8WW35	Human	PMID:26044572
Molecular Function	GO:0005515	protein binding	DYNC2I1	IPI	UniProtKB:Q9Y266	Human	PMID:27173435
Cellular Component	GO:0005813	centrosome	DYNC2I1	IDA		Human	PMID:25830415
Cellular Component	GO:0005813	centrosome	DYNC2I1	IDA		Human	PMID:31451806
Cellular Component	GO:0097546	ciliary base	DYNC2I1	IDA		Human	PMID:25830415
Cellular Component	GO:0097546	ciliary base	DYNC2I1	IDA		Human	PMID:23910462
Cellular Component	GO:0005929	cilium	Dync2i1	IDA		Mouse	PMID:22326026
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I1	IDA		Human	PMID:25205765
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I1	IDA		Human	PMID:25830415
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I1	IDA		Human	PMID:31451806
Cellular Component	GO:0005615	extracellular space	DYNC2I1	HDA		Human	PMID:22664934
Cellular Component	GO:0031021	interphase microtubule organizing center	DYNC2I1	IDA		Human	PMID:25830415
Cellular Component	GO:0000242	pericentriolar material	DYNC2I1	IDA		Human	PMID:25205765
Cellular Component	GO:0000922	spindle pole	DYNC2I1	IDA		Human	PMID:25830415
Biological Process	GO:0060271	cilium assembly	DYNC2I1	IMP		Human	PMID:23910462
Biological Process	GO:0060271	cilium assembly	DYNC2I1	IGI	UniProtKB:Q96EX3	Human	PMID:25205765
Biological Process	GO:0060271	cilium assembly	DYNC2I1	IMP		Human	PMID:25205765
Biological Process	GO:0060271	cilium assembly	DYNC2I1	IMP		Human	PMID:25830415
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	DYNC2I1	IMP		Human	PMID:23910462
Biological Process	GO:0035721	intraciliary retrograde transport	DYNC2I1	IDA		Human	PMID:29742051
Biological Process	GO:0035721	intraciliary retrograde transport	DYNC2I1	IDA		Human	PMID:30649997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern