Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSTN
  • Mouse genes Dstn
  • Rat genes Dstn
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dstn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	DSTN	IDA		Human	PMID:11812157
Molecular Function	GO:0051015	actin filament binding	DSTN	IDA		Human	PMID:8399167
Molecular Function	GO:0051015	actin filament binding	Dstn	IDA		Mouse	MGI:MGI:5784994|PMID:11809832
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P60709	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P63261	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P60709	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P63261	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q1KLZ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q549N0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P60709	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P60709	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P60709	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:P63261	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DSTN	IPI	UniProtKB:Q9Y281	Human	PMID:32296183
Cellular Component	GO:0030864	cortical actin cytoskeleton	Dstn	IDA		Mouse	PMID:15548599
Cellular Component	GO:0005737	cytoplasm	Dstn	IDA		Mouse	PMID:15548599
Cellular Component	GO:0070062	extracellular exosome	DSTN	HDA		Human	PMID:19056867
Biological Process	GO:0030042	actin filament depolymerization	DSTN	IDA		Human	PMID:11812157
Biological Process	GO:0030042	actin filament depolymerization	Dstn	IDA		Mouse	MGI:MGI:5784994|PMID:11809832
Biological Process	GO:0030043	actin filament fragmentation	Dstn	IDA		Mouse	MGI:MGI:5784994|PMID:11809832
Biological Process	GO:0000910	cytokinesis	Dstn	IMP		Mouse	PMID:15548599
Biological Process	GO:0030836	positive regulation of actin filament depolymerization	Dstn	IMP		Mouse	PMID:15548599

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern