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Gene Ontology Browser
Term Detail
GO term:cytokinesis
Synonym: cell cycle cytokinesis
Synonym: cytokinesis involved in cell cycle
GO id:GO:0000910
Alternate id: GO:0007104, GO:0033205, GO:0016288
Definition:The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
CommentsNote that when annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-aactin filament reorganization involved in cell cycle
                                                is-aactomyosin contractile ring assembly actin filament organization +
                                                is-aattachment of spindle microtubules to kinetochore +
                                                is-acell cycle arrest +
                                                is-acell cycle checkpoint +
                                                is-acell cycle DNA replication +
                                                is-acell cycle DNA replication DNA ligation +
                                                is-acell cycle DNA replication DNA unwinding +
                                                is-acell cycle DNA replication initiation +
                                                is-acell cycle DNA replication maintenance of fidelity +
                                                is-acell cycle DNA replication termination +
                                                is-acell cycle phase transition +
                                                is-acell cycle switching +
                                                is-acentriole elongation +
                                                is-acentriole replication +
                                                is-acentromere separation +
                                                is-acentrosome cycle +
                                                is-acentrosome duplication +
                                                is-acentrosome separation +
                                                is-achromosome attachment to the nuclear envelope +
                                                is-achromosome movement towards spindle pole +
                                                is-achromosome separation +
                                                is-acohesin localization to chromatin +
                                                is-acytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                        is-aCdv-dependent cytokinesis
                                                        part-ofcell septum assembly +
                                                        part-ofcytokinesis, site selection +
                                                        part-ofcytokinetic process +
                                                        is-acytoskeleton-dependent cytokinesis +
                                                        is-aFtsZ-dependent cytokinesis +
                                                        negatively-regulatesnegative regulation of cytokinesis +
                                                        positively-regulatespositive regulation of cytokinesis +
                                                        regulatesregulation of cytokinesis +
                                                        part-ofregulation of protein localization to cell division site involved in cytokinesis
                                                is-acytokinetic process +
                                                is-aDNA replication preinitiation complex assembly +
                                                is-aDNA strand elongation involved in cell cycle DNA replication +
                                                is-aestablishment of sister chromatid cohesion +
                                                is-aG0 to G1 transition +
                                                is-aG1 to G0 transition +
                                                is-ainterphase microtubule nucleation by interphase microtubule organizing center
                                                is-amaintenance of protein location in spindle pole body
                                                is-amaintenance of sister chromatid cohesion +
                                                is-ameiotic cell cycle process +
                                                is-amicrotubule anchoring at spindle pole body +
                                                is-amitotic cell cycle process +
                                                is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                                negatively-regulatesnegative regulation of cell cycle process +
                                                is-anuclear chromosome segregation +
                                                positively-regulatespositive regulation of cell cycle process +
                                                is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                                is-aprotein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +
                                                is-are-entry into mitotic cell cycle +
                                                regulatesregulation of cell cycle process +
                                                is-aregulation of syncytial blastoderm mitotic cell cycle +
                                                is-asecondary cell wall biogenesis involved in seed trichome differentiation
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asister chromatid cohesion +
                                                is-aspindle elongation +
                                                is-aspindle localization +
                                                is-aspindle midzone assembly +
                                                is-aspindle organization +
                                                is-aspindle pole body organization +
                                                is-aspindle pole body separation +
                                                is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                                is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-aactin filament reorganization involved in cell cycle
                                        is-aactomyosin contractile ring assembly actin filament organization +
                                        is-aattachment of spindle microtubules to kinetochore +
                                        is-acell cycle arrest +
                                        is-acell cycle checkpoint +
                                        is-acell cycle DNA replication +
                                        is-acell cycle DNA replication DNA ligation +
                                        is-acell cycle DNA replication DNA unwinding +
                                        is-acell cycle DNA replication initiation +
                                        is-acell cycle DNA replication maintenance of fidelity +
                                        is-acell cycle DNA replication termination +
                                        is-acell cycle phase transition +
                                        is-acell cycle switching +
                                        is-acentriole elongation +
                                        is-acentriole replication +
                                        is-acentromere separation +
                                        is-acentrosome cycle +
                                        is-acentrosome duplication +
                                        is-acentrosome separation +
                                        is-achromosome attachment to the nuclear envelope +
                                        is-achromosome movement towards spindle pole +
                                        is-achromosome separation +
                                        is-acohesin localization to chromatin +
                                        is-acytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                is-aCdv-dependent cytokinesis
                                                part-ofcell septum assembly +
                                                part-ofcytokinesis, site selection +
                                                part-ofcytokinetic process +
                                                is-acytoskeleton-dependent cytokinesis +
                                                is-aFtsZ-dependent cytokinesis +
                                                negatively-regulatesnegative regulation of cytokinesis +
                                                positively-regulatespositive regulation of cytokinesis +
                                                regulatesregulation of cytokinesis +
                                                part-ofregulation of protein localization to cell division site involved in cytokinesis
                                        is-acytokinetic process +
                                        is-aDNA replication preinitiation complex assembly +
                                        is-aDNA strand elongation involved in cell cycle DNA replication +
                                        is-aestablishment of sister chromatid cohesion +
                                        is-aG0 to G1 transition +
                                        is-aG1 to G0 transition +
                                        is-ainterphase microtubule nucleation by interphase microtubule organizing center
                                        is-amaintenance of protein location in spindle pole body
                                        is-amaintenance of sister chromatid cohesion +
                                        is-ameiotic cell cycle process +
                                        is-amicrotubule anchoring at spindle pole body +
                                        is-amitotic cell cycle process +
                                        is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                        negatively-regulatesnegative regulation of cell cycle process +
                                        is-anuclear chromosome segregation +
                                        positively-regulatespositive regulation of cell cycle process +
                                        is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                        is-aprotein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +
                                        is-are-entry into mitotic cell cycle +
                                        regulatesregulation of cell cycle process +
                                        is-aregulation of syncytial blastoderm mitotic cell cycle +
                                        is-asecondary cell wall biogenesis involved in seed trichome differentiation
                                        is-asignal transduction involved in cell cycle checkpoint +
                                        is-asister chromatid cohesion +
                                        is-aspindle elongation +
                                        is-aspindle localization +
                                        is-aspindle midzone assembly +
                                        is-aspindle organization +
                                        is-aspindle pole body organization +
                                        is-aspindle pole body separation +
                                        is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                        is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell division
                                        is-aanticlinal cell division
                                        is-aasymmetric cell division +
                                        is-acell budding +
                                        part-ofcell separation after cytokinesis +
                                        part-ofcytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                is-aCdv-dependent cytokinesis
                                                part-ofcell septum assembly +
                                                part-ofcytokinesis, site selection +
                                                part-ofcytokinetic process +
                                                is-acytoskeleton-dependent cytokinesis +
                                                is-aFtsZ-dependent cytokinesis +
                                                negatively-regulatesnegative regulation of cytokinesis +
                                                positively-regulatespositive regulation of cytokinesis +
                                                regulatesregulation of cytokinesis +
                                                part-ofregulation of protein localization to cell division site involved in cytokinesis
                                        is-aembryonic cleavage
                                        is-aepidermal cell division +
                                        is-aforebrain ventricular zone progenitor cell division +
                                        is-aglioblast division +
                                        is-agrowth plate cartilage chondrocyte division +
                                        is-amyoblast division
                                        negatively-regulatesnegative regulation of cell division +
                                        is-apericlinal cell division
                                        positively-regulatespositive regulation of cell division +
                                        is-aradial glial cell division in forebrain +
                                        is-aradial glial cell division in pallium
                                        regulatesregulation of cell division +
                                        is-aschizogony
                                        is-aspermatocyte division
                                        is-aspermatogonial cell division
                                        is-astem cell division +
                                        is-asymmetric cell division +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-aactin filament reorganization involved in cell cycle
                                                is-aactomyosin contractile ring assembly actin filament organization +
                                                is-aattachment of spindle microtubules to kinetochore +
                                                is-acell cycle arrest +
                                                is-acell cycle checkpoint +
                                                is-acell cycle DNA replication +
                                                is-acell cycle DNA replication DNA ligation +
                                                is-acell cycle DNA replication DNA unwinding +
                                                is-acell cycle DNA replication initiation +
                                                is-acell cycle DNA replication maintenance of fidelity +
                                                is-acell cycle DNA replication termination +
                                                is-acell cycle phase transition +
                                                is-acell cycle switching +
                                                is-acentriole elongation +
                                                is-acentriole replication +
                                                is-acentromere separation +
                                                is-acentrosome cycle +
                                                is-acentrosome duplication +
                                                is-acentrosome separation +
                                                is-achromosome attachment to the nuclear envelope +
                                                is-achromosome movement towards spindle pole +
                                                is-achromosome separation +
                                                is-acohesin localization to chromatin +
                                                is-acytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                        is-aCdv-dependent cytokinesis
                                                        part-ofcell septum assembly +
                                                        part-ofcytokinesis, site selection +
                                                        part-ofcytokinetic process +
                                                        is-acytoskeleton-dependent cytokinesis +
                                                        is-aFtsZ-dependent cytokinesis +
                                                        negatively-regulatesnegative regulation of cytokinesis +
                                                        positively-regulatespositive regulation of cytokinesis +
                                                        regulatesregulation of cytokinesis +
                                                        part-ofregulation of protein localization to cell division site involved in cytokinesis
                                                is-acytokinetic process +
                                                is-aDNA replication preinitiation complex assembly +
                                                is-aDNA strand elongation involved in cell cycle DNA replication +
                                                is-aestablishment of sister chromatid cohesion +
                                                is-aG0 to G1 transition +
                                                is-aG1 to G0 transition +
                                                is-ainterphase microtubule nucleation by interphase microtubule organizing center
                                                is-amaintenance of protein location in spindle pole body
                                                is-amaintenance of sister chromatid cohesion +
                                                is-ameiotic cell cycle process +
                                                is-amicrotubule anchoring at spindle pole body +
                                                is-amitotic cell cycle process +
                                                is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                                negatively-regulatesnegative regulation of cell cycle process +
                                                is-anuclear chromosome segregation +
                                                positively-regulatespositive regulation of cell cycle process +
                                                is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                                is-aprotein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +
                                                is-are-entry into mitotic cell cycle +
                                                regulatesregulation of cell cycle process +
                                                is-aregulation of syncytial blastoderm mitotic cell cycle +
                                                is-asecondary cell wall biogenesis involved in seed trichome differentiation
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asister chromatid cohesion +
                                                is-aspindle elongation +
                                                is-aspindle localization +
                                                is-aspindle midzone assembly +
                                                is-aspindle organization +
                                                is-aspindle pole body organization +
                                                is-aspindle pole body separation +
                                                is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                                is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-aactin filament reorganization involved in cell cycle
                                        is-aactomyosin contractile ring assembly actin filament organization +
                                        is-aattachment of spindle microtubules to kinetochore +
                                        is-acell cycle arrest +
                                        is-acell cycle checkpoint +
                                        is-acell cycle DNA replication +
                                        is-acell cycle DNA replication DNA ligation +
                                        is-acell cycle DNA replication DNA unwinding +
                                        is-acell cycle DNA replication initiation +
                                        is-acell cycle DNA replication maintenance of fidelity +
                                        is-acell cycle DNA replication termination +
                                        is-acell cycle phase transition +
                                        is-acell cycle switching +
                                        is-acentriole elongation +
                                        is-acentriole replication +
                                        is-acentromere separation +
                                        is-acentrosome cycle +
                                        is-acentrosome duplication +
                                        is-acentrosome separation +
                                        is-achromosome attachment to the nuclear envelope +
                                        is-achromosome movement towards spindle pole +
                                        is-achromosome separation +
                                        is-acohesin localization to chromatin +
                                        is-acytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                is-aCdv-dependent cytokinesis
                                                part-ofcell septum assembly +
                                                part-ofcytokinesis, site selection +
                                                part-ofcytokinetic process +
                                                is-acytoskeleton-dependent cytokinesis +
                                                is-aFtsZ-dependent cytokinesis +
                                                negatively-regulatesnegative regulation of cytokinesis +
                                                positively-regulatespositive regulation of cytokinesis +
                                                regulatesregulation of cytokinesis +
                                                part-ofregulation of protein localization to cell division site involved in cytokinesis
                                        is-acytokinetic process +
                                        is-aDNA replication preinitiation complex assembly +
                                        is-aDNA strand elongation involved in cell cycle DNA replication +
                                        is-aestablishment of sister chromatid cohesion +
                                        is-aG0 to G1 transition +
                                        is-aG1 to G0 transition +
                                        is-ainterphase microtubule nucleation by interphase microtubule organizing center
                                        is-amaintenance of protein location in spindle pole body
                                        is-amaintenance of sister chromatid cohesion +
                                        is-ameiotic cell cycle process +
                                        is-amicrotubule anchoring at spindle pole body +
                                        is-amitotic cell cycle process +
                                        is-amyosin filament organization involved in cytokinetic actomyosin contractile ring assembly
                                        negatively-regulatesnegative regulation of cell cycle process +
                                        is-anuclear chromosome segregation +
                                        positively-regulatespositive regulation of cell cycle process +
                                        is-apre-replicative complex assembly involved in cell cycle DNA replication +
                                        is-aprotein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly +
                                        is-are-entry into mitotic cell cycle +
                                        regulatesregulation of cell cycle process +
                                        is-aregulation of syncytial blastoderm mitotic cell cycle +
                                        is-asecondary cell wall biogenesis involved in seed trichome differentiation
                                        is-asignal transduction involved in cell cycle checkpoint +
                                        is-asister chromatid cohesion +
                                        is-aspindle elongation +
                                        is-aspindle localization +
                                        is-aspindle midzone assembly +
                                        is-aspindle organization +
                                        is-aspindle pole body organization +
                                        is-aspindle pole body separation +
                                        is-asynthesis of RNA primer involved in cell cycle DNA replication +
                                        is-atelomere maintenance via semi-conservative replication +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell division
                                        is-aanticlinal cell division
                                        is-aasymmetric cell division +
                                        is-acell budding +
                                        part-ofcell separation after cytokinesis +
                                        part-ofcytokinesis [GO:0000910] (116 genes, 146 annotations)
                                                is-aCdv-dependent cytokinesis
                                                part-ofcell septum assembly +
                                                part-ofcytokinesis, site selection +
                                                part-ofcytokinetic process +
                                                is-acytoskeleton-dependent cytokinesis +
                                                is-aFtsZ-dependent cytokinesis +
                                                negatively-regulatesnegative regulation of cytokinesis +
                                                positively-regulatespositive regulation of cytokinesis +
                                                regulatesregulation of cytokinesis +
                                                part-ofregulation of protein localization to cell division site involved in cytokinesis
                                        is-aembryonic cleavage
                                        is-aepidermal cell division +
                                        is-aforebrain ventricular zone progenitor cell division +
                                        is-aglioblast division +
                                        is-agrowth plate cartilage chondrocyte division +
                                        is-amyoblast division
                                        negatively-regulatesnegative regulation of cell division +
                                        is-apericlinal cell division
                                        positively-regulatespositive regulation of cell division +
                                        is-aradial glial cell division in forebrain +
                                        is-aradial glial cell division in pallium
                                        regulatesregulation of cell division +
                                        is-aschizogony
                                        is-aspermatocyte division
                                        is-aspermatogonial cell division
                                        is-astem cell division +
                                        is-asymmetric cell division +


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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory