Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSP
  • Mouse genes Dsp
  • Rat genes Dsp
  • Zfish genes dspa,dspb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dsp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q13835-2	Human	PMID:10852826
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q13835	Human	PMID:11790773
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q99959	Human	PMID:11790773
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q9UMD9	Human	PMID:12482924
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:P14923	Human	PMID:16917092
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q02413	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q02487	Human	PMID:21062920
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:Q15691	Human	PMID:25225338
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:P07332	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	DSP	IPI	UniProtKB:P07332	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Dsp	IPI	UniProtKB:Q4VAE3	Mouse	MGI:MGI:5699931|PMID:26403541
Molecular Function	GO:0005515	protein binding	Dsp	IPI	UniProtKB:Q3UIJ9	Mouse	MGI:MGI:4947500|PMID:20093627
Molecular Function	GO:0005080	protein kinase C binding	DSP	IPI	UniProtKB:P04409	Human	PMID:18474624
Molecular Function	GO:0003723	RNA binding	DSP	HDA		Human	PMID:22658674
Molecular Function	GO:0097110	scaffold protein binding	DSP	IPI	UniProtKB:Q13835	Human	PMID:10852826
Cellular Component	GO:0005912	adherens junction	Dsp	IDA		Mouse	MGI:MGI:3056846|PMID:15479741
Cellular Component	GO:0016323	basolateral plasma membrane	Dsp	IDA		Mouse	PMID:12951053
Cellular Component	GO:0005911	cell-cell junction	Dsp	IDA		Mouse	PMID:9864371
Cellular Component	GO:0005911	cell-cell junction	Dsp	IDA		Mouse	PMID:19001636
Cellular Component	GO:0001533	cornified envelope	DSP	IDA		Human	PMID:10908733
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Mouse	MGI:MGI:3056846|PMID:15479741
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Mouse	MGI:MGI:5805359|PMID:25617501
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Mouse	PMID:16418220
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Mouse	PMID:18496566
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Mouse	PMID:14673151
Cellular Component	GO:0030057	desmosome	Dsp	IDA		Rat	PMID:16406610|RGD:1581654
Cellular Component	GO:0070062	extracellular exosome	DSP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DSP	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	DSP	HDA		Human	PMID:20458337
Cellular Component	GO:0005916	fascia adherens	Dsp	IDA		Rat	PMID:16406610|RGD:1581654
Cellular Component	GO:0014704	intercalated disc	DSP	IDA		Human	PMID:22781308
Cellular Component	GO:0014704	intercalated disc	DSP	IDA		Human	PMID:22889254
Cellular Component	GO:0014704	intercalated disc	DSP	IDA		Human	PMID:23381804
Cellular Component	GO:0014704	intercalated disc	Dsp	IDA		Mouse	MGI:MGI:5699931|PMID:26403541
Cellular Component	GO:0014704	intercalated disc	Dsp	IDA		Mouse	PMID:17535849
Cellular Component	GO:0005882	intermediate filament	Dsp	IDA		Mouse	MGI:MGI:3723417|PMID:16917092
Cellular Component	GO:0005634	nucleus	DSP	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	DSP	IDA		Human	PMID:11790773
Cellular Component	GO:0005886	plasma membrane	DSP	IDA		Human	PMID:16917092
Cellular Component	GO:0005886	plasma membrane	DSP	IDA		Human	PMID:20859650
Cellular Component	GO:0005886	plasma membrane	Dsp	IDA		Mouse	MGI:MGI:5699931|PMID:26403541
Biological Process	GO:0034332	adherens junction organization	Dsp	IMP	MGI:MGI:1926500,MGI:MGI:2156542	Mouse	PMID:11781569
Biological Process	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	DSP	IMP		Human	PMID:12373648
Biological Process	GO:0098609	cell-cell adhesion	Dsp	IMP	MGI:MGI:2182575	Mouse	PMID:9864371
Biological Process	GO:0098609	cell-cell adhesion	Dsp	IMP	MGI:MGI:1926500,MGI:MGI:2156542	Mouse	PMID:11781569
Biological Process	GO:0002934	desmosome organization	Dsp	IMP		Mouse	MGI:MGI:3723417|PMID:16917092
Biological Process	GO:0002934	desmosome organization	Dsp	IMP	MGI:MGI:2182575	Mouse	PMID:9864371
Biological Process	GO:0090136	epithelial cell-cell adhesion	DSP	IMP		Human	PMID:27892606
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	Dsp	IMP	MGI:MGI:2182575	Mouse	PMID:9864371
Biological Process	GO:0045109	intermediate filament organization	Dsp	IMP		Mouse	MGI:MGI:3723417|PMID:16917092
Biological Process	GO:0030216	keratinocyte differentiation	DSP	IDA		Human	PMID:10908733
Biological Process	GO:0018149	peptide cross-linking	DSP	IDA		Human	PMID:10908733
Biological Process	GO:0150105	protein localization to cell-cell junction	Dsp	IMP		Mouse	MGI:MGI:3723417|PMID:16917092
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	DSP	IMP		Human	PMID:12373648
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	DSP	IMP		Human	PMID:12373648
Biological Process	GO:0043588	skin development	Dsp	IMP	MGI:MGI:1926500,MGI:MGI:2156542	Mouse	PMID:11781569
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	Dsp	IMP		Mouse	MGI:MGI:3723417|PMID:16917092
Biological Process	GO:0042060	wound healing	Dsp	IEP		Rat	PMID:11125272|RGD:1581657

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern