Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOK7
  • Mouse genes Dok7
  • Rat genes Dok7
  • Zfish genes dok7a,dok7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dok7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	Dok7	IDA		Mouse	MGI:MGI:4820894|PMID:20603078
Molecular Function	GO:0005515	protein binding	DOK7	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dok7	IPI	UniProtKB:Q61006	Mouse	MGI:MGI:5619467|PMID:20371544
Molecular Function	GO:0005515	protein binding	Dok7	IPI	UniProtKB:Q61006	Mouse	MGI:MGI:4820894|PMID:20603078
Molecular Function	GO:0005515	protein binding	Dok7	IPI	PR:Q61006	Mouse	PMID:16794080
Molecular Function	GO:0019901	protein kinase binding	DOK7	IDA		Human	PMID:20603078
Molecular Function	GO:0019901	protein kinase binding	Dok7	IDA		Mouse	MGI:MGI:4820894|PMID:20603078
Cellular Component	GO:0005739	mitochondrion	DOK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031594	neuromuscular junction	Dok7	IDA		Mouse	PMID:16794080
Cellular Component	GO:0005654	nucleoplasm	DOK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Dok7	IGI	MGI:MGI:103581	Mouse	MGI:MGI:3630229|PMID:16794080
Biological Process	GO:0007528	neuromuscular junction development	Dok7	IDA		Mouse	PMID:16794080
Biological Process	GO:0007528	neuromuscular junction development	Dok7	IGI	MGI:MGI:103581	Mouse	PMID:16794080
Biological Process	GO:0007528	neuromuscular junction development	dok7b	IMP	ZFIN:ZDB-MRPHLNO-100602-6	Zfish	PMID:20147321
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Dok7	IMP		Mouse	PMID:16794080
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	DOK7	IDA		Human	PMID:20603078
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	Dok7	IDA		Mouse	MGI:MGI:4820894|PMID:20603078
Biological Process	GO:0006468	protein phosphorylation	Dok7	IMP		Mouse	PMID:16794080
Biological Process	GO:0043113	receptor clustering	Dok7	IGI	MGI:MGI:103581	Mouse	PMID:16794080
Biological Process	GO:0043113	receptor clustering	Dok7	IDA		Mouse	PMID:16794080
Biological Process	GO:0048741	skeletal muscle fiber development	dok7b	IMP	ZFIN:ZDB-MRPHLNO-100602-6	Zfish	PMID:20147321
Biological Process	GO:0007416	synapse assembly	dok7b	IMP	ZFIN:ZDB-MRPHLNO-100602-6	Zfish	PMID:29462491
Biological Process	GO:0001966	thigmotaxis	dok7b	IMP	ZFIN:ZDB-MRPHLNO-100602-6	Zfish	PMID:29462491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern