Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOCK5
  • Mouse genes Dock5
  • Rat genes Dock5
  • Zfish genes dock5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dock5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dock5	IDA		Mouse	MGI:MGI:3784815|PMID:18396277
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dock5	IDA		Mouse	PMID:27505886
Molecular Function	GO:0005515	protein binding	DOCK5	IPI	UniProtKB:P46108	Human	PMID:19004829
Molecular Function	GO:0005515	protein binding	DOCK5	IPI	UniProtKB:P46109	Human	PMID:19004829
Molecular Function	GO:0005515	protein binding	DOCK5	IPI	UniProtKB:P46108	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	DOCK5	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Dock5	IPI	PR:Q5SSZ5	Mouse	PMID:27505886
Molecular Function	GO:0005515	protein binding	Dock5	IPI	PR:Q8BPU7	Mouse	PMID:27505886
Cellular Component	GO:0005737	cytoplasm	Dock5	IDA		Mouse	MGI:MGI:3784815|PMID:18396277
Cellular Component	GO:0005829	cytosol	DOCK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	DOCK5	IDA		Human	PMID:19004829
Cellular Component	GO:0002102	podosome	Dock5	IDA		Mouse	PMID:27505886
Biological Process	GO:0046849	bone remodeling	Dock5	IMP		Mouse	PMID:27505886
Biological Process	GO:0007520	myoblast fusion	dock5	IMP	ZFIN:ZDB-MRPHLNO-080109-12	Zfish	PMID:17670792
Biological Process	GO:0007520	myoblast fusion	dock5	IMP	ZFIN:ZDB-MRPHLNO-080109-11	Zfish	PMID:17670792
Biological Process	GO:1904694	negative regulation of vascular associated smooth muscle contraction	DOCK5	IMP		Human	PMID:22158624
Biological Process	GO:0071800	podosome assembly	Dock5	IMP		Mouse	PMID:27505886
Biological Process	GO:0010634	positive regulation of epithelial cell migration	DOCK5	IMP		Human	PMID:19004829
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	DOCK5	IMP		Human	PMID:19004829
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	DOCK5	IMP		Human	PMID:22158624
Biological Process	GO:0016601	Rac protein signal transduction	Dock5	IDA		Mouse	PMID:27505886

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern