Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOC2A
  • Mouse genes Doc2a
  • Rat genes Doc2a
  • Zfish genes doc2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Doc2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DOC2A	IPI	UniProtKB:B2RUP2	Human	PMID:18354201
Molecular Function	GO:0005515	protein binding	DOC2A	IPI	UniProtKB:Q8TF42	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	DOC2A	IPI	UniProtKB:Q8TF42	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DOC2A	IPI	UniProtKB:Q8TF42	Human	PMID:32296183
Cellular Component	GO:0030054	cell junction	DOC2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Doc2a	IDA		Rat	PMID:9115738|RGD:1357915
Cellular Component	GO:0098978	glutamatergic synapse	Doc2a	IDA		Rat	PMID:22036572|RGD:155230732
Cellular Component	GO:0098978	glutamatergic synapse	Doc2a	IMP		Rat	PMID:22036572|RGD:155230732
Cellular Component	GO:0005764	lysosome	Doc2a	IDA		Rat	PMID:18354201|RGD:8554104
Cellular Component	GO:0005730	nucleolus	DOC2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DOC2A	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	doc2a	IMP	ZFIN:ZDB-MRPHLNO-121211-4	Zfish	PMID:22566537
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Doc2a	IDA		Mouse	PMID:20150444
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Doc2a	IMP		Mouse	PMID:20150444
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Doc2a	IDA		Rat	PMID:22036572|RGD:155230732
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Doc2a	IMP		Rat	PMID:22036572|RGD:155230732
Biological Process	GO:0035264	multicellular organism growth	doc2a	IGI	ZFIN:ZDB-GENO-180306-1	Zfish	PMID:28934389
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	DOC2A	IMP		Human	PMID:18354201
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Doc2a	IMP		Mouse	MGI:MGI:3778349|PMID:18354201
Biological Process	GO:0061669	spontaneous neurotransmitter secretion	Doc2a	IDA		Mouse	PMID:21521611
Biological Process	GO:0061669	spontaneous neurotransmitter secretion	Doc2a	IGI	MGI:MGI:102788,MGI:MGI:1100497,MGI:MGI:1926250	Mouse	PMID:21521611
Biological Process	GO:0016079	synaptic vesicle exocytosis	Doc2a	IEP		Rat	PMID:10651871|RGD:1357914

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern