Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJC3
  • Mouse genes Dnajc3
  • Rat genes Dnajc3
  • Zfish genes dnajc3a,dnajc3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnajc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051787	misfolded protein binding	Dnajc3	IDA		Mouse	MGI:MGI:4418606|PMID:18923430
Molecular Function	GO:0005515	protein binding	Dnajc3	IPI	UniProtKB:P11021	Mouse	MGI:MGI:4418606|PMID:18923430
Molecular Function	GO:0019901	protein kinase binding	Dnajc3	IPI	UniProtKB:Q9QZ05	Mouse	MGI:MGI:5617428|PMID:25329545
Molecular Function	GO:0019901	protein kinase binding	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Molecular Function	GO:0004860	protein kinase inhibitor activity	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Molecular Function	GO:0051087	protein-folding chaperone binding	Dnajc3	IDA		Mouse	MGI:MGI:3692677|PMID:16923392
Molecular Function	GO:0051087	protein-folding chaperone binding	Dnajc3	IPI	UniProtKB:P20029	Mouse	MGI:MGI:4418606|PMID:18923430
Cellular Component	GO:0005737	cytoplasm	Dnajc3	IDA		Mouse	PMID:8666242
Cellular Component	GO:0005829	cytosol	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Cellular Component	GO:0005783	endoplasmic reticulum	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Dnajc3	IDA		Mouse	MGI:MGI:4418606|PMID:18923430
Cellular Component	GO:0070062	extracellular exosome	DNAJC3	HDA		Human	PMID:19199708
Cellular Component	GO:1903561	extracellular vesicle	DNAJC3	HDA		Human	PMID:24769233
Cellular Component	GO:0016020	membrane	DNAJC3	HDA		Human	PMID:19946888
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Dnajc3	IDA		Rat	PMID:22665516|RGD:8553430
Biological Process	GO:0070417	cellular response to cold	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Biological Process	GO:0043066	negative regulation of apoptotic process	DNAJC3	IMP		Human	PMID:22064321
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	DNAJC3	IMP		Human	PMID:22064321
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Biological Process	GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress	Dnajc3	IDA		Mouse	MGI:MGI:5617428|PMID:25329545
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	Dnajc3	IDA		Mouse	MGI:MGI:4418606|PMID:18923430
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Dnajc3	IMP		Mouse	MGI:MGI:3692677|PMID:16923392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern