Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJC10
  • Mouse genes Dnajc10
  • Rat genes Dnajc10
  • Zfish genes dnajc10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnajc10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	Dnajc10	IMP		Mouse	MGI:MGI:2449875|PMID:12446677
Molecular Function	GO:0051117	ATPase binding	DNAJC10	IPI	UniProtKB:P11021	Human	PMID:12411443
Molecular Function	GO:0051117	ATPase binding	Dnajc10	IPI	UniProtKB:P07823	Mouse	MGI:MGI:2449875|PMID:12446677
Molecular Function	GO:0015036	disulfide oxidoreductase activity	Dnajc10	IDA		Mouse	MGI:MGI:4943381|PMID:18653895
Molecular Function	GO:0030544	Hsp70 protein binding	DNAJC10	IPI	UniProtKB:P11021	Human	PMID:23769672
Molecular Function	GO:0051787	misfolded protein binding	DNAJC10	IDA		Human	PMID:18400946
Molecular Function	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	Dnajc10	IDA		Mouse	MGI:MGI:4947480|PMID:21329881
Molecular Function	GO:0005515	protein binding	DNAJC10	IPI	UniProtKB:Q8IWF2	Human	PMID:19706418
Molecular Function	GO:0005515	protein binding	DNAJC10	IPI	UniProtKB:Q5HYA8	Human	PMID:19815549
Molecular Function	GO:0005515	protein binding	Dnajc10	IPI	UniProtKB:Q925U4	Mouse	MGI:MGI:4947480|PMID:21329881
Molecular Function	GO:0015035	protein-disulfide reductase activity	DNAJC10	IDA		Human	PMID:23769672
Molecular Function	GO:0015035	protein-disulfide reductase activity	Dnajc10	IDA		Mouse	MGI:MGI:4947480|PMID:21329881
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJC10	IDA		Human	PMID:12411443
Molecular Function	GO:0051087	protein-folding chaperone binding	Dnajc10	IDA		Mouse	MGI:MGI:4943381|PMID:18653895
Cellular Component	GO:0005783	endoplasmic reticulum	DNAJC10	IDA		Human	PMID:12411443
Cellular Component	GO:0005783	endoplasmic reticulum	Dnajc10	IDA		Mouse	MGI:MGI:2449875|PMID:12446677
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	DNAJC10	IDA		Human	PMID:18400946
Cellular Component	GO:0005788	endoplasmic reticulum lumen	DNAJC10	IDA		Human	PMID:23769672
Cellular Component	GO:0016020	membrane	DNAJC10	HDA		Human	PMID:19946888
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	DNAJC10	IDA		Human	PMID:19122239
Biological Process	GO:0001933	negative regulation of protein phosphorylation	DNAJC10	IDA		Human	PMID:19122239
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	Dnajc10	IMP		Mouse	MGI:MGI:2449875|PMID:12446677
Biological Process	GO:0034975	protein folding in endoplasmic reticulum	DNAJC10	IDA		Human	PMID:23769672
Biological Process	GO:0034976	response to endoplasmic reticulum stress	DNAJC10	IDA		Human	PMID:19122239
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	DNAJC10	IMP		Human	PMID:18400946
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Dnajc10	IDA		Mouse	MGI:MGI:4947480|PMID:21329881
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Dnajc10	IDA		Mouse	MGI:MGI:4943381|PMID:18653895

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern