Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMXL2
  • Mouse genes Dmxl2
  • Rat genes Dmxl2
  • Zfish genes dmxl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmxl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031267	small GTPase binding	DMXL2	IDA		Human	PMID:11809763
Cellular Component	GO:0005615	extracellular space	DMXL2	HDA		Human	PMID:22664934
Cellular Component	GO:0098992	neuronal dense core vesicle	Dmxl2	IDA		Mouse	PMID:25248098
Cellular Component	GO:0008021	synaptic vesicle	DMXL2	IDA		Human	PMID:11809763
Cellular Component	GO:0008021	synaptic vesicle	Dmxl2	IDA		Rat	PMID:11809763|RGD:11058596
Biological Process	GO:0007420	brain development	Dmxl2	IMP	MGI:4432280	Mouse	PMID:29078390
Biological Process	GO:0007268	chemical synaptic transmission	Dmxl2	IMP	MGI:MGI:4432280	Mouse	PMID:30735494
Biological Process	GO:0022038	corpus callosum development	Dmxl2	IMP	MGI:4432280	Mouse	PMID:29078390
Biological Process	GO:0042593	glucose homeostasis	Dmxl2	IMP	MGI:MGI:4432280	Mouse	PMID:30735494
Biological Process	GO:0001755	neural crest cell migration	dmxl2	IMP	ZFIN:ZDB-MRPHLNO-150113-6	Zfish	PMID:24802872
Biological Process	GO:0001755	neural crest cell migration	dmxl2	IMP	ZFIN:ZDB-MRPHLNO-150113-7	Zfish	PMID:24802872
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	dmxl2	IMP	ZFIN:ZDB-MRPHLNO-150113-6	Zfish	PMID:24802872
Biological Process	GO:0030100	regulation of endocytosis	dmxl2	IMP	ZFIN:ZDB-MRPHLNO-150113-6	Zfish	PMID:24802872
Biological Process	GO:1901546	regulation of synaptic vesicle lumen acidification	dmxl2	IMP	ZFIN:ZDB-GENO-121018-2	Zfish	PMID:22875945
Biological Process	GO:0007608	sensory perception of smell	Dmxl2	IMP	MGI:MGI:4432280	Mouse	PMID:30735494
Biological Process	GO:0007283	spermatogenesis	Dmxl2	IMP	MGI:MGI:4432280	Mouse	PMID:30735494

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern