Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DGKD
  • Mouse genes Dgkd
  • Rat genes Dgkd
  • Zfish genes si:dkey-172j4.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dgkd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKD	IDA		Human	PMID:12200442
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKD	IDA		Human	PMID:17880279
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKD	IDA		Human	PMID:23949095
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgkd	IMP		Mouse	MGI:MGI:3691361|PMID:17021016
Molecular Function	GO:0042802	identical protein binding	DGKD	IPI	UniProtKB:Q16760	Human	PMID:12200442
Molecular Function	GO:0019900	kinase binding	DGKD	IPI	UniProtKB:Q86XP1-1	Human	PMID:12810723
Molecular Function	GO:0005515	protein binding	DGKD	IPI	UniProtKB:P17427	Human	PMID:17880279
Molecular Function	GO:0046982	protein heterodimerization activity	DGKD	IDA		Human	PMID:12200442
Molecular Function	GO:0042803	protein homodimerization activity	DGKD	IDA		Human	PMID:12200442
Cellular Component	GO:0005905	clathrin-coated pit	DGKD	IDA		Human	PMID:17880279
Cellular Component	GO:0005737	cytoplasm	DGKD	IDA		Human	PMID:12200442
Cellular Component	GO:0005829	cytosol	DGKD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	DGKD	IDA		Human	PMID:12200442
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKD	IDA		Human	PMID:12200442
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKD	IDA		Human	PMID:17880279
Biological Process	GO:0046339	diacylglycerol metabolic process	DGKD	IDA		Human	PMID:23949095
Biological Process	GO:0046339	diacylglycerol metabolic process	Dgkd	IMP		Mouse	MGI:MGI:3691361|PMID:17021016
Biological Process	GO:0046834	lipid phosphorylation	DGKD	IDA		Human	PMID:17880279
Biological Process	GO:0046834	lipid phosphorylation	DGKD	IDA		Human	PMID:23949095
Biological Process	GO:0046834	lipid phosphorylation	Dgkd	IMP		Mouse	MGI:MGI:3691361|PMID:17021016
Biological Process	GO:0090038	negative regulation of protein kinase C signaling	Dgkd	IMP		Mouse	MGI:MGI:3691361|PMID:17021016
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	DGKD	IDA		Human	PMID:17880279
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	DGKD	IDA		Human	PMID:23949095
Biological Process	GO:2000370	positive regulation of clathrin-dependent endocytosis	DGKD	IMP		Human	PMID:17880279
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	Dgkd	IMP		Mouse	MGI:MGI:3691361|PMID:17021016
Biological Process	GO:0010033	response to organic substance	DGKD	IDA		Human	PMID:12200442

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern