Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dgat1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DGAT1
- Mouse genes Dgat1
- Rat genes Dgat1
- Zfish genes dgat1a,dgat1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dgat1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003846	2-acylglycerol O-acyltransferase activity	Dgat1	IDA		Mouse	PMID:12077311
Molecular Function	GO:0016746	acyltransferase activity	Dgat1	IMP		Rat	PMID:18768481\|RGD:10400848
Molecular Function	GO:0019992	diacylglycerol binding	Dgat1	IDA		Rat	PMID:14596837\|RGD:1625586
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	DGAT1	IDA		Human	PMID:18458083
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	DGAT1	IDA		Human	PMID:32433610
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	DGAT1	IDA		Human	PMID:32433611
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	Dgat1	IDA		Mouse	MGI:MGI:2151970\|PMID:11481335
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	Dgat1	IDA		Rat	PMID:12193544\|RGD:628375
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	Dgat1	IDA		Rat	PMID:14596837\|RGD:1625586
Molecular Function	GO:0005504	fatty acid binding	Dgat1	IDA		Rat	PMID:14596837\|RGD:1625586
Molecular Function	GO:0042802	identical protein binding	DGAT1	IPI	UniProtKB:O75907	Human	PMID:32433610
Molecular Function	GO:0042802	identical protein binding	DGAT1	IPI	UniProtKB:O75907	Human	PMID:32433611
Molecular Function	GO:0005515	protein binding	DGAT1	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23420847
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Dgat1	IMP		Mouse	MGI:MGI:3778742\|PMID:18252207
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Dgat1	IDA		Rat	PMID:14596837\|RGD:1625586
Cellular Component	GO:0016020	membrane	DGAT1	IDA		Human	PMID:32433610
Cellular Component	GO:0016020	membrane	DGAT1	IDA		Human	PMID:32433611
Cellular Component	GO:0016020	membrane	Dgat1	IDA		Mouse	MGI:MGI:1855734\|PMID:10802663
Cellular Component	GO:0016020	membrane	Dgat1	IDA		Mouse	MGI:MGI:2151970\|PMID:11481335
Cellular Component	GO:0016020	membrane	Dgat1	IDA		Mouse	PMID:12077311
Cellular Component	GO:0005886	plasma membrane	Dgat1	IDA		Rat	PMID:18768481\|RGD:10400848
Biological Process	GO:0046339	diacylglycerol metabolic process	DGAT1	IDA		Human	PMID:32433610
Biological Process	GO:0046339	diacylglycerol metabolic process	DGAT1	IDA		Human	PMID:32433611
Biological Process	GO:0046339	diacylglycerol metabolic process	Dgat1	IDA		Mouse	MGI:MGI:2151970\|PMID:11481335
Biological Process	GO:0055089	fatty acid homeostasis	Dgat1	IGI	UniProtKB:Q9Z2A7	Mouse	MGI:MGI:3778742\|PMID:18252207
Biological Process	GO:0055089	fatty acid homeostasis	Dgat1	IMP		Mouse	MGI:MGI:1855734\|PMID:10802663
Biological Process	GO:0046486	glycerolipid metabolic process	Dgat1	IDA		Rat	PMID:12193544\|RGD:628375
Biological Process	GO:0030073	insulin secretion	Dgat1	IMP		Rat	PMID:12193544\|RGD:628375
Biological Process	GO:1902224	ketone body metabolic process	Dgat1	IMP		Rat	PMID:23449193\|RGD:10400846
Biological Process	GO:0019915	lipid storage	Dgat1	IGI	UniProtKB:Q9DCV3	Mouse	MGI:MGI:5306738\|PMID:21317108
Biological Process	GO:0019915	lipid storage	Dgat1	IMP		Mouse	MGI:MGI:1855734\|PMID:10802663
Biological Process	GO:0035336	long-chain fatty-acyl-CoA metabolic process	Dgat1	IDA		Mouse	MGI:MGI:2151970\|PMID:11481335
Biological Process	GO:0006640	monoacylglycerol biosynthetic process	DGAT1	IDA		Human	PMID:28420705
Biological Process	GO:0006640	monoacylglycerol biosynthetic process	Dgat1	IMP		Mouse	MGI:MGI:5906070\|PMID:28420705
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	Dgat1	IMP		Rat	PMID:23449193\|RGD:10400846
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	Dgat1	IMP		Rat	PMID:18000880\|RGD:10400849
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Dgat1	IMP		Rat	PMID:23449193\|RGD:10400846
Biological Process	GO:1903998	regulation of eating behavior	Dgat1	IMP		Rat	PMID:23449193\|RGD:10400846
Biological Process	GO:1904729	regulation of intestinal lipid absorption	Dgat1	IMP		Rat	PMID:18768481\|RGD:10400848
Biological Process	GO:1901738	regulation of vitamin A metabolic process	Dgat1	IMP		Rat	PMID:18000880\|RGD:10400849
Biological Process	GO:0044752	response to human chorionic gonadotropin	Dgat1	IEP		Rat	PMID:17032584\|RGD:10400844
Biological Process	GO:0001878	response to yeast	dgat1b	IDA		Zfish	PMID:23947337
Biological Process	GO:0019432	triglyceride biosynthetic process	DGAT1	IDA		Human	PMID:18458083
Biological Process	GO:0019432	triglyceride biosynthetic process	DGAT1	IDA		Human	PMID:18238778
Biological Process	GO:0019432	triglyceride biosynthetic process	DGAT1	IDA		Human	PMID:32433610
Biological Process	GO:0019432	triglyceride biosynthetic process	DGAT1	IDA		Human	PMID:32433611
Biological Process	GO:0019432	triglyceride biosynthetic process	Dgat1	IDA		Mouse	MGI:MGI:2151970\|PMID:11481335
Biological Process	GO:0019432	triglyceride biosynthetic process	Dgat1	IMP		Mouse	MGI:MGI:1855734\|PMID:10802663
Biological Process	GO:0019432	triglyceride biosynthetic process	Dgat1	IDA		Mouse	MGI:MGI:3036977\|PMID:14668353
Biological Process	GO:0019432	triglyceride biosynthetic process	Dgat1	IDA		Rat	PMID:14596837\|RGD:1625586
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	DGAT1	IMP		Human	PMID:15308631

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.