Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DFFA
  • Mouse genes Dffa
  • Rat genes Dffa
  • Zfish genes dffa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dffa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0060703	deoxyribonuclease inhibitor activity	DFFA	IMP		Human	PMID:19944011
Molecular Function	GO:0060090	molecular adaptor activity	DFFA	EXP		Human	PMID:11371636
Molecular Function	GO:0005515	protein binding	DFFA	IPI	UniProtKB:O76075	Human	PMID:11371636
Molecular Function	GO:0005515	protein binding	DFFA	IPI	UniProtKB:O76075	Human	PMID:19882353
Molecular Function	GO:0005515	protein binding	DFFA	IPI	UniProtKB:O54788	Human	PMID:22727028
Molecular Function	GO:0005515	protein binding	DFFA	IPI	UniProtKB:P04792	Human	PMID:25277244
Molecular Function	GO:0005515	protein binding	DFFA	IPI	UniProtKB:O76075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dffa	IPI	UniProtKB:O54788	Mouse	MGI:MGI:5508707|PMID:22727028
Molecular Function	GO:0005515	protein binding	Dffa	IPI	UniProtKB:O54788	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0019904	protein domain specific binding	DFFA	IPI	UniProtKB:O76075	Human	PMID:11371636
Molecular Function	GO:0044183	protein folding chaperone	DFFA	IPI	UniProtKB:O76075	Human	PMID:19944011
Cellular Component	GO:0000785	chromatin	DFFA	IDA		Human	PMID:19882353
Cellular Component	GO:0005829	cytosol	DFFA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	DFFA	IDA		Human	PMID:22253444
Cellular Component	GO:0005829	cytosol	DFFA	IDA		Human	PMID:9108473
Cellular Component	GO:0005634	nucleus	DFFA	IDA		Human	PMID:15572351
Cellular Component	GO:0005634	nucleus	Dffa	IDA		Rat	PMID:10984476|RGD:632505
Cellular Component	GO:0005886	plasma membrane	DFFA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	DFFA	IDA		Human	PMID:11371636
Biological Process	GO:0061077	chaperone-mediated protein folding	DFFA	IMP		Human	PMID:19944011
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	DFFA	IDA		Human	PMID:15572351
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	DFFA	IDA		Human	PMID:11371636
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	Dffa	IMP	MGI:MGI:2179456	Mouse	PMID:14663139
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	Dffa	IMP	MGI:MGI:2179456	Mouse	PMID:10601318
Biological Process	GO:0032076	negative regulation of deoxyribonuclease activity	DFFA	IMP		Human	PMID:19944011
Biological Process	GO:1900118	negative regulation of execution phase of apoptosis	DFFA	IDA		Human	PMID:9564035
Biological Process	GO:0043065	positive regulation of apoptotic process	Dffa	IMP	MGI:MGI:2179456	Mouse	PMID:14663139
Biological Process	GO:0070242	thymocyte apoptotic process	Dffa	IMP	MGI:MGI:2179456	Mouse	PMID:10601318

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern