Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DENND5A
  • Mouse genes Dennd5a
  • Rat genes Dennd5a
  • Zfish genes dennd5a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dennd5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	DENND5A	IDA		Human	PMID:20937701
Molecular Function	GO:0005515	protein binding	DENND5A	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dennd5a	IPI	UniProtKB:P20340	Mouse	MGI:MGI:4418603|PMID:19141279
Molecular Function	GO:0005515	protein binding	Dennd5a	IPI	UniProtKB:P20340-1	Mouse	MGI:MGI:4418603|PMID:19141279
Molecular Function	GO:0031267	small GTPase binding	Dennd5a	IDA		Mouse	PMID:7631419
Cellular Component	GO:0005794	Golgi apparatus	Dennd5a	IDA		Mouse	MGI:MGI:4418603|PMID:19141279
Cellular Component	GO:0005802	trans-Golgi network	DENND5A	IDA		Human	PMID:19619496
Biological Process	GO:0010977	negative regulation of neuron projection development	Dennd5a	IMP		Rat	PMID:27866705|RGD:12859078
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	DENND5A	IMP		Human	PMID:19619496

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern