Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DENND3
  • Mouse genes Dennd3
  • Rat genes Dennd3
  • Zfish genes dennd3a,dennd3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dennd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	DENND3	IDA		Human	PMID:20937701
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dennd3	IGI		Mouse	MGI:MGI:5448516|PMID:21718402
Biological Process	GO:0008333	endosome to lysosome transport	Dennd3	IGI		Mouse	MGI:MGI:5448516|PMID:21718402
Biological Process	GO:0048484	enteric nervous system development	dennd3a	IGI	ZFIN:ZDB-CRISPR-170419-1,ZFIN:ZDB-CRISPR-170816-2	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	dennd3a	IGI	ZFIN:ZDB-MRPHLNO-170419-18,ZFIN:ZDB-MRPHLNO-170419-19	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	dennd3a	IGI	ZFIN:ZDB-MRPHLNO-170419-5,ZFIN:ZDB-MRPHLNO-170419-6	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	dennd3b	IGI	ZFIN:ZDB-MRPHLNO-170419-18,ZFIN:ZDB-MRPHLNO-170419-19	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	dennd3b	IGI	ZFIN:ZDB-CRISPR-170419-1,ZFIN:ZDB-CRISPR-170816-2	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	dennd3b	IGI	ZFIN:ZDB-MRPHLNO-170419-5,ZFIN:ZDB-MRPHLNO-170419-6	Zfish	PMID:28274275
Biological Process	GO:0030163	protein catabolic process	Dennd3	IMP		Mouse	MGI:MGI:5448516|PMID:21718402

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern