Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DENND1B
  • Mouse genes Dennd1b
  • Rat genes Dennd1b
  • Zfish genes dennd1b,dennd1c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dennd1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	DENND1B	IDA		Human	PMID:20937701
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822
Molecular Function	GO:0031267	small GTPase binding	Dennd1b	IPI	UniProtKB:Q6PHN9	Mouse	MGI:MGI:5751612|PMID:26774822
Cellular Component	GO:0005829	cytosol	DENND1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	DENND1B	IDA		Human	GO_REF:0000052
Biological Process	GO:0032456	endocytic recycling	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822
Biological Process	GO:0043547	positive regulation of GTPase activity	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	DENND1B	IMP		Human	PMID:26774822
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822
Biological Process	GO:0050776	regulation of immune response	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822
Biological Process	GO:0050852	T cell receptor signaling pathway	DENND1B	IMP		Human	PMID:26774822
Biological Process	GO:0050852	T cell receptor signaling pathway	Dennd1b	IMP		Mouse	MGI:MGI:5751612|PMID:26774822

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern