Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DEFB103A,DEFB103B
  • Mouse genes Defb14
  • Rat genes Defb14
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Defb14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042056	chemoattractant activity	Defb14	IDA		Mouse	PMID:18167348
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q2M2E3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q8IWB4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DEFB103A	IPI	UniProtKB:Q9Y2C3	Human	PMID:32296183
Cellular Component	GO:0005615	extracellular space	DEFB103A	IDA		Human	PMID:21115716
Biological Process	GO:0060326	cell chemotaxis	Defb14	IDA		Mouse	PMID:18167348
Biological Process	GO:0042742	defense response to bacterium	DEFB103A	IMP		Human	PMID:21115716
Biological Process	GO:0042742	defense response to bacterium	Defb14	IDA		Mouse	PMID:18167348
Biological Process	GO:0050829	defense response to Gram-negative bacterium	DEFB103A	IDA		Human	PMID:15625724
Biological Process	GO:0050830	defense response to Gram-positive bacterium	DEFB103A	IDA		Human	PMID:15625724
Biological Process	GO:0051873	killing by host of symbiont cells	DEFB103A	IDA		Human	PMID:16436752
Biological Process	GO:0031640	killing of cells of another organism	DEFB103A	IDA		Human	PMID:15625724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern