Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDT,DDTL
  • Mouse genes Ddt
  • Rat genes Ddt
  • Zfish genes ddt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005126	cytokine receptor binding	DDT	IDA		Human	PMID:21817065
Molecular Function	GO:0033981	D-dopachrome decarboxylase activity	DDT	IDA		Human	PMID:8267597
Molecular Function	GO:0033981	D-dopachrome decarboxylase activity	DDT	IMP		Human	PMID:9480844
Molecular Function	GO:0033981	D-dopachrome decarboxylase activity	Ddt	IDA		Rat	PMID:8267597|RGD:151356628
Molecular Function	GO:0050178	phenylpyruvate tautomerase activity	DDT	IDA		Human	PMID:21817065
Molecular Function	GO:0002020	protease binding	Ddt	IPI	UniProtKB:O35864	Mouse	MGI:MGI:5286754|PMID:21817065
Cellular Component	GO:0070062	extracellular exosome	DDTL	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	DDT	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DDT	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	DDT	IDA		Human	PMID:21817065
Cellular Component	GO:0005615	extracellular space	Ddt	IDA		Mouse	MGI:MGI:5286754|PMID:21817065
Biological Process	GO:0048839	inner ear development	ddt	IGI	ZFIN:ZDB-MRPHLNO-120323-3,ZFIN:ZDB-MRPHLNO-120323-4,ZFIN:ZDB-MRPHLNO-120323-5	Zfish	PMID:22210003
Biological Process	GO:0043066	negative regulation of apoptotic process	ddt	IGI	ZFIN:ZDB-MRPHLNO-120323-3,ZFIN:ZDB-MRPHLNO-120323-4,ZFIN:ZDB-MRPHLNO-120323-5	Zfish	PMID:22210003
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	DDT	IDA		Human	PMID:21817065
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	DDT	IGI	UniProtKB:P14174	Human	PMID:21817065
Biological Process	GO:0050729	positive regulation of inflammatory response	Ddt	IMP		Mouse	MGI:MGI:5286754|PMID:21817065
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	DDT	IDA		Human	PMID:21817065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern