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Ddt Gene Detail
Summary
  • Symbol
    Ddt
  • Name
    D-dopachrome tautomerase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298381
    NCBI Gene: 13202
  • Gene Overview
    MyGene.info: DDT
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:75771233-75773374 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 38.58 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298381
protein coding gene Chr10:75771230-75773414 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017362
protein coding gene Chr10:75956845-75959028 (-)
A/J MGP_AJ_G0017339
protein coding gene Chr10:73350360-73352540 (-)
AKR/J MGP_AKRJ_G0017300
protein coding gene Chr10:75315170-75317353 (-)
BALB/cJ MGP_BALBcJ_G0017299
protein coding gene Chr10:73546062-73548242 (-)
C3H/HeJ MGP_C3HHeJ_G0017123
protein coding gene Chr10:75354293-75356477 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017757
protein coding gene Chr10:78642808-78646597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015447
protein coding gene Chr10:69803961-69806172 (-)
CAST/EiJ MGP_CASTEiJ_G0016694
protein coding gene Chr10:75674941-75677115 (-)
CBA/J MGP_CBAJ_G0017095
protein coding gene Chr10:81712574-81714758 (-)
DBA/2J MGP_DBA2J_G0017200
protein coding gene Chr10:72652065-72654247 (-)
FVB/NJ MGP_FVBNJ_G0017193
protein coding gene Chr10:71800537-71802717 (-)
LP/J MGP_LPJ_G0017273
protein coding gene Chr10:76461472-76465016 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017221
protein coding gene Chr10:83805952-83808135 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017796
protein coding gene Chr10:75348209-75350395 (-)
PWK/PhJ MGP_PWKPhJ_G0016477
protein coding gene Chr10:72477796-72479974 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016260
protein coding gene Chr10:74588317-74590571 (-)
WSB/EiJ MGP_WSBEiJ_G0016757
protein coding gene Chr10:75320524-75322708 (-)



Homology
more
  • Human Ortholog
    DDT, D-dopachrome tautomerase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DDT, D-dopachrome tautomerase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDCT, D-DT, MIF2, MIF-2
  • Links
    NCBI Gene ID: 1652
    neXtProt AC: NX_P30046
    UniProt: P30046

  • Chr Location
    22q11.23; chr22:23971365-23979828 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 1038
    1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DDT
  • Gene Tree
    Ddt
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13202 NCBI Gene Model | MGI Sequence Detail 2142 C57BL/6J ±  kb
transcript NM_010027 RefSeq | MGI Sequence Detail 609 Not Specified  
polypeptide O35215 UniProt | EBI | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 118
    Genomic 12
    cDNA 106

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143922
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:264602 Gamer LW, et al., The Role of Bmp2 in the Maturation and Maintenance of the Murine Knee Joint. J Bone Miner Res. 2018 Sep;33(9):1708-1717

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory