Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ddrgk1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DDRGK1
- Mouse genes Ddrgk1
- Rat genes Ddrgk1
- Zfish genes ddrgk1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddrgk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:O94874	Human	PMID:20018847
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:Q9Y3C8	Human	PMID:20018847
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:Q96JB5	Human	PMID:20228063
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:P25963	Human	PMID:23675531
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:Q15650	Human	PMID:25219498
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:O75460	Human	PMID:28128204
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:P48436	Human	PMID:28263186
Molecular Function	GO:0005515	protein binding	DDRGK1	IPI	UniProtKB:O94874	Human	PMID:32160526
Molecular Function	GO:0005515	protein binding	Ddrgk1	IPI	UniProtKB:P20029\|UniProtKB:P61961	Mouse	MGI:MGI:5613470\|PMID:21494687
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	DDRGK1	IDA		Human	PMID:23675531
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	DDRGK1	IPI	UniProtKB:O94874	Human	PMID:25219498
Cellular Component	GO:0005783	endoplasmic reticulum	DDRGK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	DDRGK1	IDA		Human	PMID:20018847
Cellular Component	GO:0005783	endoplasmic reticulum	Ddrgk1	IDA		Mouse	MGI:MGI:5613470\|PMID:21494687
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DDRGK1	IDA		Human	PMID:20228063
Cellular Component	GO:0005789	endoplasmic reticulum membrane	DDRGK1	IDA		Human	PMID:32160526
Cellular Component	GO:0005730	nucleolus	DDRGK1	IDA		Human	GO_REF:0000052
Biological Process	GO:0051216	cartilage development	DDRGK1	IMP		Human	PMID:28263186
Biological Process	GO:0051216	cartilage development	Ddrgk1	IMP		Mouse	MGI:MGI:5908314\|PMID:28263186
Biological Process	GO:0051216	cartilage development	ddrgk1	IMP	ZFIN:ZDB-MRPHLNO-170531-2	Zfish	PMID:28263186
Biological Process	GO:0043066	negative regulation of apoptotic process	Ddrgk1	IMP		Rat	PMID:21494687\|RGD:11567254
Biological Process	GO:0010629	negative regulation of gene expression	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	DDRGK1	IDA		Human	PMID:28128204
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	DDRGK1	IDA		Human	PMID:32160526
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	Ddrgk1	IMP		Mouse	MGI:MGI:5912977\|PMID:28128204
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	DDRGK1	IMP		Human	PMID:28263186
Biological Process	GO:0030335	positive regulation of cell migration	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:0008284	positive regulation of cell population proliferation	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:0010628	positive regulation of gene expression	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1903721	positive regulation of I-kappaB phosphorylation	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1905050	positive regulation of metallopeptidase activity	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1905552	positive regulation of protein localization to endoplasmic reticulum	Ddrgk1	IDA		Mouse	MGI:MGI:5613470\|PMID:21494687
Biological Process	GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DDRGK1	IMP		Human	PMID:23675531
Biological Process	GO:1990592	protein K69-linked ufmylation	DDRGK1	IDA		Human	PMID:25219498
Biological Process	GO:0070972	protein localization to endoplasmic reticulum	DDRGK1	IDA		Human	PMID:32160526
Biological Process	GO:0071569	protein ufmylation	DDRGK1	IDA		Human	PMID:32160526
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	DDRGK1	IDA		Human	PMID:25219498
Biological Process	GO:0031647	regulation of protein stability	DDRGK1	IDA		Human	PMID:28128204
Biological Process	GO:0034976	response to endoplasmic reticulum stress	DDRGK1	IDA		Human	PMID:28128204
Biological Process	GO:0034976	response to endoplasmic reticulum stress	DDRGK1	IDA		Human	PMID:32160526
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ddrgk1	IMP		Mouse	MGI:MGI:5613470\|PMID:21494687
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ddrgk1	IMP		Mouse	MGI:MGI:5912977\|PMID:28128204
Biological Process	GO:0061709	reticulophagy	DDRGK1	IDA		Human	PMID:32160526

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.