Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDI2
  • Mouse genes Ddi2
  • Rat genes Ddi2
  • Zfish genes ddi2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddi2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	DDI2	IDA		Human	PMID:27528193
Molecular Function	GO:0042802	identical protein binding	DDI2	IDA		Human	PMID:27461074
Molecular Function	GO:0005515	protein binding	DDI2	IPI	UniProtKB:Q14494:PRO_0000076447	Human	PMID:27528193
Molecular Function	GO:0005515	protein binding	DDI2	IPI	UniProtKB:P04844|UniProtKB:P12004|UniProtKB:P15927|UniProtKB:P48556|UniProtKB:P55036|UniProtKB:Q14566	Human	PMID:29290612
Molecular Function	GO:0005515	protein binding	DDI2	IPI	UniProtKB:Q9BY42	Human	PMID:29290612
Molecular Function	GO:0043130	ubiquitin binding	DDI2	IDA		Human	PMID:27461074
Cellular Component	GO:0005829	cytosol	DDI2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DDI2	IDA		Human	GO_REF:0000052
Biological Process	GO:0072711	cellular response to hydroxyurea	DDI2	IMP		Human	PMID:29290612
Biological Process	GO:0010498	proteasomal protein catabolic process	DDI2	IMP		Human	PMID:29290612
Biological Process	GO:0016485	protein processing	DDI2	IDA		Human	PMID:27528193
Biological Process	GO:0016485	protein processing	DDI2	IMP		Human	PMID:27676298
Biological Process	GO:0097752	regulation of DNA stability	DDI2	IMP		Human	PMID:29290612
Biological Process	GO:0031647	regulation of protein stability	DDI2	IMP		Human	PMID:29290612

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern