Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCXR
  • Mouse genes Dcxr
  • Rat genes Dcxr
  • Zfish genes dcxr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcxr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	DCXR	IPI	UniProtKB:Q7Z4W1	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	DCXR	IPI	UniProtKB:Q7Z4W1	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	DCXR	IPI	UniProtKB:Q7Z4W1	Human	PMID:32296183
Molecular Function	GO:0050038	L-xylulose reductase (NADP+) activity	DCXR	IDA		Human	PMID:11882650
Molecular Function	GO:0050038	L-xylulose reductase (NADP+) activity	Dcxr	IDA		Mouse	PMID:11882650
Molecular Function	GO:0050038	L-xylulose reductase (NADP+) activity	Dcxr	IDA		Rat	PMID:11882650|RGD:632676
Molecular Function	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	Dcxr	IDA		Mouse	PMID:11882650
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	DCXR	IDA		Human	PMID:19442656
Molecular Function	GO:0005515	protein binding	DCXR	IPI	UniProtKB:Q9NS18	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dcxr	IPI	PR:Q91X52	Mouse	PMID:11882650
Cellular Component	GO:0005903	brush border	Dcxr	IDA		Mouse	PMID:11882650
Cellular Component	GO:0005881	cytoplasmic microtubule	DCXR	IDA		Human	PMID:23264731
Cellular Component	GO:0005829	cytosol	Dcxr	IDA		Mouse	PMID:38160
Cellular Component	GO:0070062	extracellular exosome	DCXR	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DCXR	HDA		Human	PMID:23533145
Cellular Component	GO:0005902	microvillus	Dcxr	IDA		Mouse	PMID:11882650
Cellular Component	GO:0005634	nucleus	DCXR	HDA		Human	PMID:21630459
Biological Process	GO:0006006	glucose metabolic process	DCXR	IDA		Human	PMID:11882650
Biological Process	GO:0006006	glucose metabolic process	Dcxr	IDA		Mouse	MGI:MGI:2179664|PMID:11882650
Biological Process	GO:0006006	glucose metabolic process	Dcxr	IDA		Rat	PMID:11882650|RGD:632676
Biological Process	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate	Dcxr	IDA		Mouse	PMID:11882650
Biological Process	GO:0006739	NADP metabolic process	Dcxr	IDA		Mouse	PMID:11882650
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	DCXR	IDA		Human	PMID:19442656
Biological Process	GO:0005997	xylulose metabolic process	DCXR	IDA		Human	PMID:11882650
Biological Process	GO:0005997	xylulose metabolic process	Dcxr	IDA		Mouse	PMID:11882650
Biological Process	GO:0005997	xylulose metabolic process	Dcxr	IDA		Rat	PMID:11882650|RGD:632676

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern