Dcxr
Gene Detail

Symbol Name ID

Dcxr dicarbonyl L-xylulose reductase MGI:1915130

Synonyms

0610038K04Rik, 1810027P18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 11

84.47 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:120725399-120727281 bp, - strand From VEGA annotation of GRCm38   1883 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22964  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dcxr

Human homologs

Human Homolog		DCXR, dicarbonyl/L-xylulose reductase
NCBI Gene ID		51181
neXtProt AC		NX_Q7Z4W1
Human Synonyms		DCR, HCR2, HCRII, KIDCR, P34H, SDR20C1, XR
Human Chr (Location)		17q25.3; chr17:79993757-79995573 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human DCXR

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (26 annotations)

Process	carbohydrate metabolic process, D-xylose metabolic process, ...
Component	brush border, cytoplasmic microtubule, ...
Function	L-xylulose reductase (NADP+) activity, oxidoreductase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(72)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(72) cDNA(72)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000004121 (Evidence)
Ensembl Gene Model	ENSMUSG00000039450 (Evidence)
Entrez Gene	67880 (Evidence)
UniGene	231091
DFCI	TC1580107, TC1602529, TC1676870
DoTS	DT.110507727, DT.493562, DT.94327822, DT.94327826, DT.94327832, DT.94327836, DT.97402070
NIA Mouse Gene Index	U033732
EC	1.1.1.10
Consensus CDS Project	CCDS25755.1
International Mouse Knockout Project Status	Dcxr

Sequences

Length	Strain/Species
genomic	OTTMUSG00000004121	VEGA Gene Model | MGI Sequence Detail	1883	C57BL/6J
transcript	OTTMUST00000009303	VEGA | MGI Sequence Detail	892	Not Applicable
polypeptide	OTTMUSP00000004527	VEGA | MGI Sequence Detail	244	Not Applicable

All sequences(45) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(9 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002347	Glucose/ribitol dehydrogenase
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR020904	Short-chain dehydrogenase/reductase, conserved site
InterPro	IPR002198	Short-chain dehydrogenase/reductase SDR
Protein Ontology	PR:000006336	L-xylulose reductase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Other accession IDs

MGI:1917589