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Dcxr Gene Detail
Summary
  • Symbol
    Dcxr
  • Name
    dicarbonyl L-xylulose reductase
  • Synonyms
    0610038K04Rik, 1810027P18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915130
    NCBI Gene: 67880
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120725399-120727281 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 84.47 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    15 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915130
protein coding gene Chr11:120725373-120727323 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019525
protein coding gene Chr11:125210307-125214054 (-)
A/J MGP_AJ_G0019493
protein coding gene Chr11:119635712-119637375 (-)
AKR/J MGP_AKRJ_G0019463
protein coding gene Chr11:123252939-123256265 (-)
BALB/cJ MGP_BALBcJ_G0019468
protein coding gene Chr11:119995269-119997617 (-)
C3H/HeJ MGP_C3HHeJ_G0019274
protein coding gene Chr11:123583052-123586032 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019916
protein coding gene Chr11:128996108-128998021 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017542
protein coding gene Chr11:116626319-116628188 (-)
CAST/EiJ MGP_CASTEiJ_G0018828
protein coding gene Chr11:125082189-125084081 (-)
CBA/J MGP_CBAJ_G0019245
protein coding gene Chr11:134032098-134033961 (-)
DBA/2J MGP_DBA2J_G0019357
protein coding gene Chr11:119003775-119006252 (-)
FVB/NJ MGP_FVBNJ_G0019349
protein coding gene Chr11:118718282-118720148 (-)
LP/J MGP_LPJ_G0019429
protein coding gene Chr11:125511820-125513684 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019382
protein coding gene Chr11:132869404-132873833 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019956
protein coding gene Chr11:123921965-123923872 (-)
PWK/PhJ MGP_PWKPhJ_G0018594
protein coding gene Chr11:120448544-120450442 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018386
protein coding gene Chr11:123691564-123693427 (-)
WSB/EiJ MGP_WSBEiJ_G0018880
protein coding gene Chr11:123920674-123922550 (-)



Homology
more
  • Human Ortholog
    DCXR, dicarbonyl and L-xylulose reductase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCXR, dicarbonyl and L-xylulose reductase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR
  • Links
    NCBI Gene ID: 51181
    neXtProt AC: NX_Q7Z4W1
    UniProt: Q7Z4W1

  • Chr Location
    17q25.3; chr17:82035881-82037697 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 22964
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DCXR
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039450 Ensembl Gene Model | MGI Sequence Detail 1883 C57BL/6J ±  kb
    transcript ENSMUST00000026144 Ensembl | MGI Sequence Detail 892 Not Applicable  
    polypeptide ENSMUSP00000026144 Ensembl | MGI Sequence Detail 244 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 73
      cDNA 73

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1917589
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:237998 Hubbs AF, et al., Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity. Am J Pathol. 2016 Nov;186(11):2887-2908

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory