About   Help   FAQ
Dcxr
Gene Detail
 Symbol
Name
ID
Dcxr
dicarbonyl L-xylulose reductase
MGI:1915130
Synonyms 0610038K04Rik, 1810027P18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
84.47 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:120725399-120727281 bp, - strand
From VEGA annotation of GRCm38

  1883 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22964  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dcxr

Human
homologs
Human Homolog DCXR, dicarbonyl/L-xylulose reductase
NCBI Gene ID 51181
neXtProt AC  NX_Q7Z4W1
Human Synonyms  DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR
Human Chr (Location)  17q25.3; chr17:82035881-82037697 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DCXR
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dcxr interacts with 19 markers (Mir27b, Mir32, Mir34a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process carbohydrate metabolic process, D-xylose metabolic process, ...
Component brush border, cytoplasmic microtubule, ...
Function L-xylulose reductase (NADP+) activity, oxidoreductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(72) cDNA(72)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000004121 (Evidence)
Ensembl Gene ModelENSMUSG00000039450 (Evidence)
Entrez Gene67880 (Evidence)
UniGene231091
DFCITC1580107, TC1602529, TC1676870
DoTSDT.110507727, DT.493562, DT.94327822, DT.94327826, DT.94327832, DT.94327836, DT.97402070
NIA Mouse Gene IndexU033732
EC1.1.1.10
Consensus CDS ProjectCCDS25755.1
International Mouse Knockout Project StatusDcxr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004121 VEGA Gene Model | MGI Sequence Detail 1883 C57BL/6J ±  kb
transcript OTTMUST00000009303 VEGA | MGI Sequence Detail 892 Not Applicable 
polypeptide OTTMUSP00000004527 VEGA | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002347 Glucose/ribitol dehydrogenase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020904 Short-chain dehydrogenase/reductase, conserved site
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
Protein Ontology PR:000006336 L-xylulose reductase
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:1917589

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory