Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCTN1
  • Mouse genes Dctn1
  • Rat genes Dctn1
  • Zfish genes dctn1a,dctn1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dctn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Dctn1	IPI	UniProtKB:P28023	Rat	PMID:25419851|RGD:13432346
Molecular Function	GO:0008017	microtubule binding	DCTN1	IMP		Human	PMID:16505168
Molecular Function	GO:0008017	microtubule binding	DCTN1	IDA		Human	PMID:23874158
Molecular Function	GO:0008017	microtubule binding	DCTN1	IDA		Human	PMID:26972003
Molecular Function	GO:0008017	microtubule binding	Dctn1	IDA		Mouse	MGI:MGI:3663261|PMID:16954346
Molecular Function	GO:0008017	microtubule binding	Dctn1	IDA		Rat	PMID:7878030|RGD:11541103
Molecular Function	GO:0060090	molecular adaptor activity	Dctn1	EXP		Rat	PMID:31445682|RGD:152995562
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P42025	Human	PMID:12857853
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q96RK4	Human	PMID:15107855
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q96G01	Human	PMID:17139249
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9UKA1	Human	PMID:17532294
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P30622	Human	PMID:17828275
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P30622-1	Human	PMID:17828275
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P30622-1	Human	PMID:17828277
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:17828277
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P10636-8	Human	PMID:17932487
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q96RK4	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P54256	Human	PMID:18615096
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P42858	Human	PMID:18922795
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q96MT3	Human	PMID:18922795
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9UNH7	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9Y5X3	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9UNH7	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P12270	Human	PMID:20133940
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P30622	Human	PMID:20679239
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P53350	Human	PMID:20679239
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9NPB6	Human	PMID:20719959
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q8N1N2	Human	PMID:20978158
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:M0R2J8	Human	PMID:22159412
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q13286	Human	PMID:22261744
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q99426	Human	PMID:22777741
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9UPN4	Human	PMID:22797915
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:G3G960	Human	PMID:23414759
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9UNH7	Human	PMID:23524952
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q8IVT2	Human	PMID:23574715
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:23874158
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9P2H0	Human	PMID:24867236
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:24997520
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q86YV9	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P10636-8	Human	PMID:26269332
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P42025	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9JK25	Human	PMID:26972003
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q15691	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:Q9P287-2	Human	PMID:28394342
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:P54256	Human	PMID:9361024
Molecular Function	GO:0005515	protein binding	DCTN1	IPI	UniProtKB:O75935	Human	PMID:9722614
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:P33175	Mouse	MGI:MGI:3804774|PMID:18615096
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:Q6A078	Mouse	MGI:MGI:3624140|PMID:16632484
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:Q921C5	Mouse	MGI:MGI:5507956|PMID:22956769
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:Q80VW7	Mouse	MGI:MGI:6294240|PMID:30787442
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:Q91ZU6-2	Mouse	MGI:MGI:2679412|PMID:14581450
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:P28741	Mouse	MGI:MGI:5559658|PMID:23386061
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	UniProtKB:Q8BLY7	Mouse	MGI:MGI:5805360|PMID:25189619
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	PR:O35668	Mouse	PMID:15242649
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	PR:P63005	Mouse	PMID:22073305
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	PR:P42859	Mouse	PMID:15242649
Molecular Function	GO:0005515	protein binding	Dctn1	IPI	PR:Q9ERR1	Mouse	PMID:18331715
Molecular Function	GO:0019901	protein kinase binding	DCTN1	IPI	UniProtKB:P49841	Human	PMID:17139249
Molecular Function	GO:0015631	tubulin binding	DCTN1	IDA		Human	PMID:23874158
Cellular Component	GO:0005938	cell cortex	DCTN1	IDA		Human	PMID:23509069
Cellular Component	GO:0005938	cell cortex	DCTN1	IDA		Human	PMID:23027904
Cellular Component	GO:0099738	cell cortex region	DCTN1	IDA		Human	PMID:22327364
Cellular Component	GO:0031252	cell leading edge	Dctn1	IDA		Mouse	PMID:18331715
Cellular Component	GO:0120103	centriolar subdistal appendage	DCTN1	IDA		Human	PMID:23213374
Cellular Component	GO:0005814	centriole	DCTN1	IDA		Human	PMID:23213374
Cellular Component	GO:0005814	centriole	DCTN1	IDA		Human	PMID:23386061
Cellular Component	GO:0005814	centriole	DCTN1	IDA		Human	PMID:25774020
Cellular Component	GO:0005814	centriole	Dctn1	IDA		Mouse	MGI:MGI:5559658|PMID:23386061
Cellular Component	GO:0005813	centrosome	DCTN1	IDA		Human	PMID:20719959
Cellular Component	GO:0005813	centrosome	DCTN1	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	DCTN1	IDA		Human	PMID:23985322
Cellular Component	GO:0005813	centrosome	DCTN1	IDA		Human	PMID:25774020
Cellular Component	GO:0036064	ciliary basal body	Dctn1	IDA		Mouse	PMID:17600711
Cellular Component	GO:0005737	cytoplasm	DCTN1	IDA		Human	PMID:18305234
Cellular Component	GO:0005868	cytoplasmic dynein complex	Dctn1	IDA		Rat	PMID:1828535|RGD:61569
Cellular Component	GO:0045171	intercellular bridge	DCTN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	DCTN1	IDA		Human	PMID:19468067
Cellular Component	GO:0000776	kinetochore	DCTN1	IDA		Human	PMID:23027904
Cellular Component	GO:0016020	membrane	DCTN1	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	DCTN1	IDA		Human	PMID:21525035
Cellular Component	GO:0005874	microtubule	DCTN1	IDA		Human	PMID:22777741
Cellular Component	GO:0005874	microtubule	DCTN1	IDA		Human	PMID:25774020
Cellular Component	GO:0005875	microtubule associated complex	DCTN1	IMP		Human	PMID:16505168
Cellular Component	GO:0015630	microtubule cytoskeleton	DCTN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035371	microtubule plus-end	DCTN1	IDA		Human	PMID:26972003
Cellular Component	GO:0035371	microtubule plus-end	Dctn1	IDA		Mouse	MGI:MGI:3663261|PMID:16954346
Cellular Component	GO:0072686	mitotic spindle	DCTN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	DCTN1	IDA		Human	PMID:18364389
Cellular Component	GO:0043025	neuronal cell body	DCTN1	IDA		Human	PMID:18364389
Cellular Component	GO:0005635	nuclear envelope	DCTN1	IDA		Human	PMID:20679239
Cellular Component	GO:0032991	protein-containing complex	Dctn1	IDA		Mouse	PMID:23523350
Cellular Component	GO:0005819	spindle	DCTN1	IDA		Human	PMID:25774020
Cellular Component	GO:0000922	spindle pole	DCTN1	IDA		Human	PMID:14718566
Cellular Component	GO:0000922	spindle pole	Dctn1	IDA		Mouse	MGI:MGI:5754878|PMID:26765568
Biological Process	GO:0045176	apical protein localization	dctn1a	IMP	ZFIN:ZDB-MRPHLNO-071201-2	Zfish	PMID:17785424
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	dctn1b	IGI	ZFIN:ZDB-MRPHLNO-090608-4,ZFIN:ZDB-MRPHLNO-100617-2	Zfish	PMID:20412557
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	dctn1a	IGI	ZFIN:ZDB-MRPHLNO-090608-4,ZFIN:ZDB-MRPHLNO-100617-2	Zfish	PMID:20412557
Biological Process	GO:0010457	centriole-centriole cohesion	DCTN1	IMP		Human	PMID:23386061
Biological Process	GO:0000132	establishment of mitotic spindle orientation	DCTN1	IMP		Human	PMID:22327364
Biological Process	GO:0032402	melanosome transport	Dctn1	IMP		Mouse	PMID:22275436
Biological Process	GO:0034454	microtubule anchoring at centrosome	DCTN1	IMP		Human	PMID:23386061
Biological Process	GO:0061744	motor behavior	DCTN1	IMP		Human	PMID:18305234
Biological Process	GO:0061744	motor behavior	DCTN1	IMP		Human	PMID:18364389
Biological Process	GO:0007528	neuromuscular junction development	DCTN1	IMP		Human	PMID:18305234
Biological Process	GO:0050905	neuromuscular process	DCTN1	IMP		Human	PMID:18305234
Biological Process	GO:0070050	neuron cellular homeostasis	DCTN1	IMP		Human	PMID:18305234
Biological Process	GO:0048663	neuron fate commitment	dctn1a	IMP	ZFIN:ZDB-GENO-090312-5	Zfish	PMID:18805097
Biological Process	GO:1990535	neuron projection maintenance	DCTN1	IMP		Human	PMID:18305234
Biological Process	GO:1990535	neuron projection maintenance	DCTN1	IMP		Human	PMID:18364389
Biological Process	GO:1905515	non-motile cilium assembly	DCTN1	IMP		Human	PMID:25774020
Biological Process	GO:0051081	nuclear membrane disassembly	DCTN1	IMP		Human	PMID:20679239
Biological Process	GO:0007097	nuclear migration	dctn1a	IMP	ZFIN:ZDB-GENO-090312-5	Zfish	PMID:18805097
Biological Process	GO:0007097	nuclear migration	dctn1a	IMP	ZFIN:ZDB-MRPHLNO-071201-2	Zfish	PMID:17785424
Biological Process	GO:0090063	positive regulation of microtubule nucleation	DCTN1	IDA		Human	PMID:23874158
Biological Process	GO:0031116	positive regulation of microtubule polymerization	DCTN1	IMP		Human	PMID:16505168
Biological Process	GO:0031116	positive regulation of microtubule polymerization	DCTN1	IDA		Human	PMID:23874158
Biological Process	GO:1904398	positive regulation of neuromuscular junction development	DCTN1	IMP		Human	PMID:18364389
Biological Process	GO:0060236	regulation of mitotic spindle organization	DCTN1	IMP		Human	PMID:23027904
Biological Process	GO:0060041	retina development in camera-type eye	dctn1a	IMP	ZFIN:ZDB-GENO-100614-1	Zfish	PMID:11517263
Biological Process	GO:0010842	retina layer formation	dctn1a	IGI	ZFIN:ZDB-GENO-090608-5	Zfish	PMID:18805097
Biological Process	GO:0010842	retina layer formation	dctn1a	IMP	ZFIN:ZDB-GENO-090312-5	Zfish	PMID:18805097
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	dctn1a	IMP	ZFIN:ZDB-GENO-090312-5	Zfish	PMID:18805097
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	DCTN1	IMP		Human	PMID:19619496
Biological Process	GO:0021517	ventral spinal cord development	DCTN1	IMP		Human	PMID:18305234

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern