Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRYM
  • Mouse genes Crym
  • Rat genes Crym
  • Zfish genes crym
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crym

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042562	hormone binding	Crym	IMP	MGI:MGI:3703787	Mouse	PMID:17264173
Molecular Function	GO:0050661	NADP binding	CRYM	IDA		Human	PMID:17242435
Molecular Function	GO:0005515	protein binding	CRYM	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	CRYM	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	CRYM	IDA		Human	PMID:12590647
Molecular Function	GO:0047127	thiomorpholine-carboxylate dehydrogenase activity	CRYM	IDA		Human	PMID:21332720
Molecular Function	GO:0070324	thyroid hormone binding	CRYM	IMP		Human	PMID:16740909
Molecular Function	GO:0070324	thyroid hormone binding	CRYM	IDA		Human	PMID:9328354
Molecular Function	GO:0003714	transcription corepressor activity	CRYM	IMP		Human	PMID:11897713
Cellular Component	GO:0005737	cytoplasm	CRYM	IDA		Human	PMID:12471561
Cellular Component	GO:0005737	cytoplasm	CRYM	IDA		Human	PMID:12590647
Cellular Component	GO:0005829	cytosol	CRYM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Crym	IDA		Rat	PMID:2984063|RGD:2303732
Cellular Component	GO:0070062	extracellular exosome	CRYM	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CRYM	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Crym	IDA		Mouse	PMID:18448257
Cellular Component	GO:0005634	nucleus	Crym	IDA		Mouse	PMID:18448257
Biological Process	GO:0006839	mitochondrial transport	Crym	IDA		Rat	PMID:3015565|RGD:2303731
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CRYM	IMP		Human	PMID:11897713
Biological Process	GO:0009725	response to hormone	Crym	IEP		Rat	PMID:2809492|RGD:2303730
Biological Process	GO:0033280	response to vitamin D	Crym	IEP		Rat	PMID:2809492|RGD:2303730
Biological Process	GO:0007605	sensory perception of sound	CRYM	IMP		Human	PMID:12471561
Biological Process	GO:0042403	thyroid hormone metabolic process	Crym	IMP	MGI:MGI:3703787	Mouse	PMID:17264173
Biological Process	GO:0070327	thyroid hormone transport	CRYM	IMP		Human	PMID:11897713

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern