Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRTC3
  • Mouse genes Crtc3
  • Rat genes Crtc3
  • Zfish genes crtc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crtc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CRTC3	IPI	UniProtKB:P62258	Human	PMID:30611118
Molecular Function	GO:0005515	protein binding	CRTC3	IPI	UniProtKB:Q8N1Q1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Crtc3	IPI	UniProtKB:P30153|UniProtKB:P62258|UniProtKB:P63151|UniProtKB:P67775	Mouse	MGI:MGI:6282941|PMID:30611118
Cellular Component	GO:0005737	cytoplasm	Crtc3	IDA		Mouse	MGI:MGI:6282941|PMID:30611118
Cellular Component	GO:0005737	cytoplasm	Crtc3	IDA		Mouse	PMID:24674967
Cellular Component	GO:0005737	cytoplasm	Crtc3	IDA		Mouse	PMID:24768298
Cellular Component	GO:0005737	cytoplasm	Crtc3	IDA		Mouse	PMID:21164481
Cellular Component	GO:0005829	cytosol	CRTC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CRTC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Crtc3	IDA		Mouse	MGI:MGI:6282941|PMID:30611118
Cellular Component	GO:0005634	nucleus	Crtc3	IDA		Mouse	PMID:21164481
Cellular Component	GO:0005634	nucleus	Crtc3	IDA		Mouse	PMID:24768298
Cellular Component	GO:0005634	nucleus	Crtc3	IDA		Mouse	PMID:24674967
Biological Process	GO:0097009	energy homeostasis	Crtc3	IMP	MGI:MGI:4879976	Mouse	PMID:21164481
Biological Process	GO:0016042	lipid catabolic process	Crtc3	IMP	MGI:MGI:4879976	Mouse	PMID:21164481
Biological Process	GO:0042116	macrophage activation	CRTC3	IMP		Human	PMID:23033494
Biological Process	GO:0071878	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Crtc3	IDA		Mouse	PMID:21164481
Biological Process	GO:0050995	negative regulation of lipid catabolic process	Crtc3	IMP	MGI:MGI:4879976	Mouse	PMID:21164481
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	Crtc3	IMP		Mouse	MGI:MGI:6282941|PMID:30611118
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc3	IDA		Mouse	PMID:21164481
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc3	IDA		Mouse	PMID:24674967
Biological Process	GO:0001666	response to hypoxia	crtc3	IMP	ZFIN:ZDB-MRPHLNO-150826-8	Zfish	PMID:25840431

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern