Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CROCC
  • Mouse genes Crocc
  • Rat genes Crocc
  • Zfish genes crocc,crocc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crocc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Crocc	IDA		Mouse	PMID:15870283
Molecular Function	GO:0019894	kinesin binding	Crocc	IPI	PR:O88448	Mouse	PMID:16018997
Molecular Function	GO:0019894	kinesin binding	Crocc	IPI	PR:Q91W40	Mouse	PMID:16018997
Molecular Function	GO:0019894	kinesin binding	Crocc	IPI	PR:O88447	Mouse	PMID:16018997
Molecular Function	GO:0005515	protein binding	CROCC	IPI	UniProtKB:P35222	Human	PMID:18086858
Molecular Function	GO:0005515	protein binding	CROCC	IPI	UniProtKB:Q68D86	Human	PMID:30404835
Molecular Function	GO:0005515	protein binding	CROCC	IPI	UniProtKB:Q9C0F1	Human	PMID:31974111
Molecular Function	GO:0005515	protein binding	Crocc	IPI	PR:P39053	Mouse	PMID:23746204
Molecular Function	GO:0005200	structural constituent of cytoskeleton	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Molecular Function	GO:0005198	structural molecule activity	Crocc	IDA		Mouse	MGI:MGI:2429967|PMID:12427867
Cellular Component	GO:0097729	9+2 motile cilium	Crocc	IDA		Mouse	PMID:29891944
Cellular Component	GO:0015629	actin cytoskeleton	CROCC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005814	centriole	CROCC	IDA		Human	PMID:24421332
Cellular Component	GO:0005814	centriole	Crocc	IDA		Mouse	MGI:MGI:3654803|PMID:16339073
Cellular Component	GO:0005813	centrosome	CROCC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	CROCC	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	CROCC	IDA		Human	PMID:31974111
Cellular Component	GO:0097546	ciliary base	crocc2	IDA		Zfish	PMID:25139857
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IDA		Mouse	PMID:29891944
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:23178122
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IDA		Mouse	PMID:16018997
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IDA		Mouse	PMID:23178122
Cellular Component	GO:0035253	ciliary rootlet	Crocc	IDA		Mouse	PMID:21212183
Cellular Component	GO:0005829	cytosol	CROCC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CROCC	HDA		Human	PMID:19056867
Cellular Component	GO:0001917	photoreceptor inner segment	Crocc	IDA		Mouse	PMID:23178122
Cellular Component	GO:0005886	plasma membrane	CROCC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0120219	subapical part of cell	Crocc	IDA		Mouse	PMID:29891944
Biological Process	GO:0019725	cellular homeostasis	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0010457	centriole-centriole cohesion	CROCC	IMP		Human	PMID:24554434
Biological Process	GO:0007098	centrosome cycle	CROCC	IDA		Human	PMID:16203858
Biological Process	GO:0032053	ciliary basal body organization	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0010669	epithelial structure maintenance	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0051649	establishment of localization in cell	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0051656	establishment of organelle localization	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0045494	photoreceptor cell maintenance	Crocc	IMP	MGI:MGI:3580447	Mouse	PMID:15870283
Biological Process	GO:0045724	positive regulation of cilium assembly	CROCC	IMP		Human	PMID:27623382
Biological Process	GO:1903566	positive regulation of protein localization to cilium	CROCC	IMP		Human	PMID:27623382
Biological Process	GO:0008104	protein localization	CROCC	IMP		Human	PMID:18086858
Biological Process	GO:0033365	protein localization to organelle	CROCC	IMP		Human	PMID:24554434

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern