Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRLF1
  • Mouse genes Crlf1
  • Rat genes Crlf1
  • Zfish genes crlf1a,crlf1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crlf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005127	ciliary neurotrophic factor receptor binding	CRLF1	IDA		Human	PMID:10966616
Molecular Function	GO:0005125	cytokine activity	CRLF1	IDA		Human	PMID:10966616
Molecular Function	GO:0019955	cytokine binding	CRLF1	IPI	UniProtKB:Q9UBD9	Human	PMID:15034937
Molecular Function	GO:0005515	protein binding	CRLF1	IPI	UniProtKB:Q9UBD9	Human	PMID:10966616
Molecular Function	GO:0005515	protein binding	CRLF1	IPI	UniProtKB:Q8NEV9	Human	PMID:19933857
Molecular Function	GO:0005515	protein binding	CRLF1	IPI	UniProtKB:Q92673	Human	PMID:26858303
Cellular Component	GO:0097058	CRLF-CLCF1 complex	CRLF1	IDA		Human	PMID:10966616
Cellular Component	GO:0005615	extracellular space	Crlf1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:2000672	negative regulation of motor neuron apoptotic process	Crlf1	IMP		Mouse	MGI:MGI:2677656|PMID:14523086
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	CRLF1	IDA		Human	PMID:10966616
Biological Process	GO:0008284	positive regulation of cell population proliferation	CRLF1	IDA		Human	PMID:10966616
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	CRLF1	IDA		Human	PMID:10966616
Biological Process	GO:0001657	ureteric bud development	Crlf1	IEP		Mouse	MGI:MGI:3655805|PMID:16545622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern