Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CORO2B
  • Mouse genes Coro2b
  • Rat genes Coro2b
  • Zfish genes coro2ba,coro2bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Coro2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CORO2B	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CORO2B	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:1990147	talin binding	CORO2B	IDA		Human	PMID:29162887
Molecular Function	GO:0017166	vinculin binding	CORO2B	IPI	UniProtKB:P18206	Human	PMID:29162887
Cellular Component	GO:0005925	focal adhesion	CORO2B	IDA		Human	PMID:29162887
Cellular Component	GO:0005925	focal adhesion	Coro2b	IDA		Mouse	PMID:29162887
Biological Process	GO:0048041	focal adhesion assembly	Coro2b	IMP	MGI:MGI:4419137	Mouse	PMID:29162887
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	CORO2B	IDA		Human	PMID:29162887
Biological Process	GO:1904950	negative regulation of establishment of protein localization	CORO2B	IDA		Human	PMID:29162887
Biological Process	GO:0051497	negative regulation of stress fiber assembly	Coro2b	IMP	MGI:MGI:4419137	Mouse	PMID:29162887
Biological Process	GO:1904951	positive regulation of establishment of protein localization	CORO2B	IDA		Human	PMID:29162887
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	CORO2B	IDA		Human	PMID:29162887
Biological Process	GO:0080135	regulation of cellular response to stress	CORO2B	IDA		Human	PMID:29162887
Biological Process	GO:0003093	regulation of glomerular filtration	Coro2b	IMP	MGI:MGI:4419137	Mouse	PMID:29162887

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern