Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COPS5
  • Mouse genes Cops5
  • Rat genes Cops5
  • Zfish genes cops5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cops5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Cops5	IPI	UniProtKB:O35215	Mouse	MGI:MGI:5286754|PMID:21817065
Molecular Function	GO:0035718	macrophage migration inhibitory factor binding	Cops5	IPI	UniProtKB:P34884	Mouse	MGI:MGI:5286754|PMID:21817065
Molecular Function	GO:0140492	metal-dependent deubiquitinase activity	COPS5	IDA		Human	PMID:19246649
Molecular Function	GO:0008237	metallopeptidase activity	COPS5	IMP		Human	PMID:19214193
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P09936	Human	PMID:12082530
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P46527	Human	PMID:12082530
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:O15105	Human	PMID:14993265
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:O75460	Human	PMID:15234121
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P10599	Human	PMID:15480426
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P46527	Human	PMID:15480426
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:O95273	Human	PMID:15887118
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:O60356	Human	PMID:16300740
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P55085	Human	PMID:16410250
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:O14879	Human	PMID:17050680
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:18850735
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:18850735
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:18850735
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q5VTR2	Human	PMID:19214193
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:19444310
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q8TC84	Human	PMID:20978819
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P10599	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9H8M7	Human	PMID:21499297
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:21625211
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q8IWQ3	Human	PMID:22609399
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q8WXC6-2	Human	PMID:23776465
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:P35372	Human	PMID:23840749
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:24421388
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:24421388
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q8WXC6	Human	PMID:26456823
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q13098	Human	PMID:27029275
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q7L5N1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q9UNS2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	COPS5	IPI	UniProtKB:Q969Y2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:O88543	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:Q9JLI7	Mouse	PMID:31146259
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:O88545	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:Q99LD4	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:Q8VBV7	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:P61202	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops5	IPI	PR:O88544	Mouse	PMID:9707402
Cellular Component	GO:0000785	chromatin	COPS5	IDA		Human	PMID:20978819
Cellular Component	GO:0008180	COP9 signalosome	COPS5	IPI		Human	PMID:25043011
Cellular Component	GO:0008180	COP9 signalosome	COPS5	IDA		Human	PMID:18850735
Cellular Component	GO:0008180	COP9 signalosome	COPS5	IDA		Human	PMID:19214193
Cellular Component	GO:0008180	COP9 signalosome	Cops5	IDA		Mouse	PMID:9707402
Cellular Component	GO:0005737	cytoplasm	COPS5	IDA		Human	PMID:16300740
Cellular Component	GO:0005737	cytoplasm	COPS5	IDA		Human	PMID:17050680
Cellular Component	GO:0005737	cytoplasm	COPS5	IDA		Human	PMID:24421388
Cellular Component	GO:0005829	cytosol	COPS5	IDA		Human	PMID:20978819
Cellular Component	GO:0005654	nucleoplasm	COPS5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	COPS5	IDA		Human	PMID:16300740
Cellular Component	GO:0005634	nucleus	COPS5	IDA		Human	PMID:17050680
Cellular Component	GO:0005634	nucleus	COPS5	IDA		Human	PMID:20978819
Cellular Component	GO:0005634	nucleus	COPS5	IDA		Human	PMID:24421388
Cellular Component	GO:0048471	perinuclear region of cytoplasm	COPS5	IDA		Human	PMID:16300740
Cellular Component	GO:0008021	synaptic vesicle	COPS5	IDA		Human	PMID:21102408
Biological Process	GO:1990182	exosomal secretion	COPS5	IDA		Human	PMID:19246649
Biological Process	GO:0043066	negative regulation of apoptotic process	COPS5	IMP		Human	PMID:20978819
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	COPS5	IDA		Human	PMID:20978819
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	COPS5	IDA		Human	PMID:16410250
Biological Process	GO:0000338	protein deneddylation	COPS5	IDA		Human	PMID:19141280
Biological Process	GO:0000338	protein deneddylation	COPS5	IMP		Human	PMID:19214193
Biological Process	GO:0016579	protein deubiquitination	COPS5	IDA		Human	PMID:19246649
Biological Process	GO:0051726	regulation of cell cycle	Cops5	IMP	MGI:MGI:3511260	Mouse	PMID:15299027
Biological Process	GO:1903894	regulation of IRE1-mediated unfolded protein response	COPS5	IMP		Human	PMID:15234121
Biological Process	GO:0046328	regulation of JNK cascade	COPS5	IDA		Human	PMID:16410250
Biological Process	GO:0060118	vestibular receptor cell development	cops5	IMP	ZFIN:ZDB-MRPHLNO-180713-1	Zfish	PMID:28928022

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern