Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLK3
  • Mouse genes Clk3
  • Rat genes Clk3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CLK3	IPI	UniProtKB:P49761	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	CLK3	IPI	UniProtKB:P49761	Human	PMID:32296183
Molecular Function	GO:0016301	kinase activity	Clk3	IDA		Rat	PMID:8679717|RGD:727235
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P49760	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BUV0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P49760	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O43463	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P62995	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O14978	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P09629	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P0DJD3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P17509	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P29728	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P38159	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P49760	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P78362	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q15415	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BUV0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P29728	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BUV0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O14492-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O75494	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:O76064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P09017	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P09629	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P10523	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P17509	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P29728-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P49760	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P62995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P84103	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q15287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q16560-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q5M9Q1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8IWX8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8N2M8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8TAD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8WTR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BRL6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9BUV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9UBU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9ULD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q9Y2P0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P62995	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q15287	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CLK3	IPI	UniProtKB:Q8N2M8	Human	PMID:32707033
Molecular Function	GO:0004672	protein kinase activity	Clk3	IDA		Rat	PMID:8679717|RGD:727235
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Clk3	IDA		Mouse	MGI:MGI:1096966|PMID:9307018
Molecular Function	GO:0004713	protein tyrosine kinase activity	Clk3	IDA		Mouse	PMID:9307018
Molecular Function	GO:0003723	RNA binding	CLK3	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CLK3	HDA		Human	PMID:22681889
Cellular Component	GO:0045111	intermediate filament cytoskeleton	CLK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CLK3	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	CLK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CLK3	IDA		Human	PMID:9637771
Cellular Component	GO:0005634	nucleus	Clk3	IDA		Mouse	PMID:9307018
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Clk3	IDA		Mouse	PMID:9307018
Biological Process	GO:0046777	protein autophosphorylation	Clk3	IDA		Mouse	PMID:9307018
Biological Process	GO:0006468	protein phosphorylation	CLK3	IDA		Human	PMID:9637771
Biological Process	GO:0006468	protein phosphorylation	Clk3	IDA		Mouse	MGI:MGI:1096966|PMID:9307018
Biological Process	GO:0043484	regulation of RNA splicing	CLK3	IDA		Human	PMID:9637771

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern