Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC4D
  • Mouse genes Clec4d
  • Rat genes Clec4d
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec4d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034987	immunoglobulin receptor binding	Clec4d	IPI	PR:P20491	Mouse	PMID:23602766
Molecular Function	GO:0005537	mannose binding	CLEC4D	IDA		Human	PMID:23911656
Molecular Function	GO:0038187	pattern recognition receptor activity	CLEC4D	IDA		Human	PMID:23911656
Molecular Function	GO:0005515	protein binding	CLEC4D	IPI	UniProtKB:Q6EIG7	Human	PMID:23911656
Molecular Function	GO:0005515	protein binding	CLEC4D	IPI	UniProtKB:P35609	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CLEC4D	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC4D	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC4D	IPI	UniProtKB:Q8N966	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Clec4d	IPI	UniProtKB:Q67EQ1	Rat	PMID:23921530|RGD:13838792
Cellular Component	GO:0005886	plasma membrane	CLEC4D	IDA		Human	PMID:23911656
Cellular Component	GO:0005886	plasma membrane	Clec4d	IDA		Mouse	PMID:23602766
Biological Process	GO:0002250	adaptive immune response	Clec4d	IMP		Mouse	PMID:23602766
Biological Process	GO:0061760	antifungal innate immune response	CLEC4D	IDA		Human	PMID:23911656
Biological Process	GO:0061760	antifungal innate immune response	Clec4d	IMP		Mouse	MGI:MGI:5562511|PMID:23911656
Biological Process	GO:0042742	defense response to bacterium	Clec4d	IMP		Mouse	PMID:23602766
Biological Process	GO:0038094	Fc-gamma receptor signaling pathway	Clec4d	IDA		Mouse	PMID:23602766
Biological Process	GO:0045087	innate immune response	Clec4d	IMP		Mouse	PMID:23602766
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Clec4d	IMP		Mouse	MGI:MGI:5562511|PMID:23911656
Biological Process	GO:0030887	positive regulation of myeloid dendritic cell activation	Clec4d	IMP		Mouse	MGI:MGI:5525050|PMID:23602766
Biological Process	GO:0002292	T cell differentiation involved in immune response	Clec4d	IMP		Mouse	PMID:23602766

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern