Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLDN8
  • Mouse genes Cldn8
  • Rat genes Cldn8
  • Zfish genes cldn8.2,cldn8.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:P35372-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q6ZS10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q8TC27	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q99640-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q9BZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN8	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cldn8	IPI	UniProtKB:O35054	Mouse	MGI:MGI:4837608|PMID:20921420
Molecular Function	GO:0005515	protein binding	Cldn8	IPI	UniProtKB:P39447|UniProtKB:Q9QXY1|UniProtKB:Q9Z0U1	Mouse	MGI:MGI:1350677|PMID:10601346
Cellular Component	GO:0016327	apicolateral plasma membrane	Cldn8	IDA		Mouse	MGI:MGI:1355488|PMID:9892664
Cellular Component	GO:0016323	basolateral plasma membrane	Cldn8	IDA		Mouse	PMID:16651389
Cellular Component	GO:0005923	bicellular tight junction	Cldn8	IDA		Mouse	MGI:MGI:1355488|PMID:9892664
Cellular Component	GO:0005923	bicellular tight junction	Cldn8	IDA		Mouse	PMID:16520537
Cellular Component	GO:0005783	endoplasmic reticulum	CLDN8	HDA		Human	PMID:16780588
Cellular Component	GO:0005886	plasma membrane	CLDN8	HDA		Human	PMID:16780588

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern