Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLDN16
  • Mouse genes Cldn16
  • Rat genes Cldn16
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLDN16	IPI	UniProtKB:Q9Z0S3	Human	PMID:22373575
Molecular Function	GO:0005515	protein binding	Cldn16	IPI	UniProtKB:O97758	Rat	PMID:15496416|RGD:1599617
Cellular Component	GO:0005923	bicellular tight junction	Cldn16	IDA		Mouse	PMID:16520537
Cellular Component	GO:0005923	bicellular tight junction	Cldn16	IDA		Rat	PMID:15496416|RGD:1599617
Biological Process	GO:0051928	positive regulation of calcium ion transport	Cldn16	IDA		Rat	PMID:15496416|RGD:1599617
Biological Process	GO:0070633	transepithelial transport	Cldn16	IDA		Rat	PMID:15496416|RGD:1599617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern