Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLCNKA,CLCNKB
  • Mouse genes Clcnkb
  • Rat genes Clcnkb
  • Zfish genes clcnk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clcnkb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	Clcnkb	IDA		Rat	PMID:8021279|RGD:1600680
Molecular Function	GO:0015108	chloride transmembrane transporter activity	clcnk	IDA		Zfish	PMID:31177533
Molecular Function	GO:0015108	chloride transmembrane transporter activity	clcnk	IGI	ZFIN:ZDB-GENE-070705-548	Zfish	PMID:31177533
Molecular Function	GO:0042802	identical protein binding	CLCNKA	IPI	UniProtKB:P51800	Human	PMID:17562318
Molecular Function	GO:0005515	protein binding	Clcnkb	IPI	UniProtKB:Q8VIM4	Mouse	MGI:MGI:3690168|PMID:11734858
Biological Process	GO:0055064	chloride ion homeostasis	clcnk	IMP	ZFIN:ZDB-GENO-200505-13	Zfish	PMID:31177533
Biological Process	GO:1902476	chloride transmembrane transport	clcnk	IDA		Zfish	PMID:31177533|ZFIN:ZDB-PUB-190610-4
Biological Process	GO:0006821	chloride transport	Clcnkb	IDA		Rat	PMID:8021279|RGD:1600680
Biological Process	GO:0070294	renal sodium ion absorption	CLCNKB	IMP		Human	PMID:9326936

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern