Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIR1
  • Mouse genes Cir1
  • Rat genes Cir1
  • Zfish genes cir1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cir1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042826	histone deacetylase binding	CIR1	IDA		Human	PMID:9874765
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q01081	Human	PMID:15652350
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q01130	Human	PMID:15652350
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q07955	Human	PMID:15652350
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q8TA86	Human	PMID:15652350
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q8N5F7	Human	PMID:19409814
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q8TAP6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:O75446	Human	PMID:9874765
Molecular Function	GO:0005515	protein binding	CIR1	IPI	UniProtKB:Q06330	Human	PMID:9874765
Molecular Function	GO:0005515	protein binding	Cir1	IPI	UniProtKB:P97762	Mouse	MGI:MGI:3688359|PMID:15652350
Molecular Function	GO:0019901	protein kinase binding	CIR1	IPI	UniProtKB:Q9HC98	Human	PMID:20873783
Molecular Function	GO:0044877	protein-containing complex binding	CIR1	IDA		Human	PMID:9874765
Molecular Function	GO:0003714	transcription corepressor activity	CIR1	IDA		Human	PMID:9874765
Cellular Component	GO:0005813	centrosome	CIR1	IDA		Human	PMID:20873783
Cellular Component	GO:0016607	nuclear speck	CIR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CIR1	IDA		Human	PMID:15652350
Cellular Component	GO:0005634	nucleus	CIR1	IDA		Human	PMID:9874765
Cellular Component	GO:0032991	protein-containing complex	CIR1	IDA		Human	PMID:20873783
Biological Process	GO:0001701	in utero embryonic development	Cir1	IMP	MGI:MGI:5577261	Mouse	PMID:27996060
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CIR1	IDA		Human	PMID:9874765
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CIR1	IDA		Human	PMID:9874765

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern