Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHIA
  • Mouse genes Chia1
  • Rat genes Chia
  • Zfish genes chia.2,chia.3,chia.4,chia.6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chia1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008061	chitin binding	Chia1	IDA		Mouse	MGI:MGI:1931335|PMID:11085997
Molecular Function	GO:0004568	chitinase activity	CHIA	IDA		Human	PMID:19435888
Molecular Function	GO:0004568	chitinase activity	Chia1	IDA		Mouse	MGI:MGI:1931335|PMID:11085997
Molecular Function	GO:0004568	chitinase activity	Chia1	IDA		Mouse	MGI:MGI:3826690|PMID:18824549
Molecular Function	GO:0004568	chitinase activity	Chia	IDA		Rat	PMID:16971062|RGD:5013834
Molecular Function	GO:0019900	kinase binding	CHIA	IPI	UniProtKB:P00533	Human	PMID:18824549
Molecular Function	GO:0005515	protein binding	CHIA	IPI	UniProtKB:P00533	Human	PMID:18824549
Molecular Function	GO:0005515	protein binding	CHIA	IPI	UniProtKB:Q5RI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHIA	IPI	UniProtKB:Q8NC74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHIA	IPI	UniProtKB:Q92609	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Chia1	IDA		Mouse	MGI:MGI:3826690|PMID:18824549
Cellular Component	GO:0005737	cytoplasm	chia.4	IDA		Zfish	PMID:25139857
Cellular Component	GO:0005576	extracellular region	Chia	IDA		Rat	PMID:16971062|RGD:5013834
Cellular Component	GO:0005615	extracellular space	CHIA	IDA		Human	PMID:18824549
Cellular Component	GO:0016020	membrane	chia.4	IDA		Zfish	PMID:25139857
Biological Process	GO:0006032	chitin catabolic process	CHIA	IDA		Human	PMID:19435888
Biological Process	GO:0006032	chitin catabolic process	Chia1	IDA		Mouse	MGI:MGI:1931335|PMID:11085997
Biological Process	GO:0006032	chitin catabolic process	Chia	IDA		Rat	PMID:11085997|RGD:5000759
Biological Process	GO:0032722	positive regulation of chemokine production	CHIA	IDA		Human	PMID:18824549
Biological Process	GO:0002532	production of molecular mediator involved in inflammatory response	CHIA	IDA		Human	PMID:18824549

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern