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Chia1 Gene Detail
Summary
  • Symbol
    Chia1
  • Name
    chitinase, acidic 1
  • Synonyms
    2200003E03Rik, AMCase, Chia, YNL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1932052
    NCBI Gene: 81600
  • Gene Overview
    MyGene.info: CHIA
Location & Maps
more
  • Sequence Map
    Chr3:106113229-106132120 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18892 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.49 cM, cytoband F3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CHIA, chitinase, acidic
  • Vertebrate Orthologs
    12
  • Human Ortholog
    CHIA, chitinase, acidic
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AMCASE, CHIT2, TSA1902
  • Links
    NCBI Gene ID: 27159
    neXtProt AC: NX_Q9BZP6

  • Chr Location
    1p13.2; chr1:111290852-111320566 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    2 involving Chia1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023684 VEGA Gene Model | MGI Sequence Detail 18892 C57BL/6J ±  kb
transcript OTTMUST00000057828 VEGA | MGI Sequence Detail 1681 Not Applicable  
polypeptide OTTMUSP00000027956 VEGA | MGI Sequence Detail 473 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    70 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 690
    cDNA 690

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913535
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:209310 Kashimura A, et al., Protein A-mouse acidic mammalian chitinase-V5-His expressed in periplasmic space of Escherichia coli possesses chitinase functions comparable to CHO-expressed protein. PLoS One. 2013;8(11):e78669

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory