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Chia1
Gene Detail
Symbol

Name
ID
Chia1
chitinase, acidic 1
MGI:1932052
Synonyms
2200003E03Rik, AMCase, Chia, YNL
Feature Type
protein coding gene
Genetic Map
Chromosome 3
46.49 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:106113229-106132120 bp, + strand
From VEGA annotation of GRCm38

  18892 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75168  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 4 zebrafish

HCOP human homology predictions: CHIA
Protein SuperFamily: chitinase-like protein
Gene Tree: Chia1

Human
homologs
CHIA, chitinase, acidic
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 27159
neXtProt AC: NX_Q9BZP6

Human Synonyms: AMCASE, CHIT2, TSA1902

Human Chr (Location): 1p13.2; chr1:111290852-111320566 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Chia1 interacts with 56 markers (Mir18, Mir18b, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process apoptotic process, carbohydrate metabolic process, ...
Component cytoplasm, extracellular region, ...
Function chitinase activity, chitin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(690)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase chia    NEW 
Molecular
reagents
All nucleic(690) cDNA(690)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023684 (Evidence)
Ensembl Gene Model ENSMUSG00000062778 (Evidence)
Entrez Gene 81600 (Evidence)
UniGene 46418
DFCI TC1573958
DoTS DT.91568021, DT.91397031
NIA Mouse Gene Index U003703
EC 3.2.1.14
Consensus CDS Project CCDS38585.1
International Mouse Phenotyping Consortium Status Chia1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023684 VEGA Gene Model | MGI Sequence Detail 18892 C57BL/6J ±  kb
transcript OTTMUST00000057828 VEGA | MGI Sequence Detail 1681 Not Applicable 
polypeptide OTTMUSP00000027956 VEGA | MGI Sequence Detail 473 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011583 Chitinase II
InterPro IPR002557 Chitin binding domain
InterPro IPR013781 Glycoside hydrolase, catalytic domain
InterPro IPR001579 Glycoside hydrolase, chitinase active site
InterPro IPR001223 Glycoside hydrolase, family 18, catalytic domain
InterPro IPR017853 Glycoside hydrolase, superfamily
Protein Ontology PR:000005425 acidic mammalian chitinase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:209310 Kashimura A, et al., Protein A-mouse acidic mammalian chitinase-V5-His expressed in periplasmic space of Escherichia coli possesses chitinase functions comparable to CHO-expressed protein. PLoS One. 2013;8(11):e78669
All references(37)
Other
accession IDs
MGI:1913535

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory