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Chia1
Gene Detail
 Symbol
Name
ID
Chia1
chitinase, acidic 1
MGI:1932052
Synonyms 2200003E03Rik, AMCase, Chia, YNL
Feature Type protein coding gene
Genetic Map
Chromosome 3
46.49 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:106113229-106132120 bp, + strand
From VEGA annotation of GRCm38

  18892 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75168  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 4 zebrafish

Protein SuperFamily: chitinase-like protein
Gene Tree: Chia1

Human
homologs
Human Homolog CHIA, chitinase, acidic
NCBI Gene ID 27159
neXtProt AC  NX_Q9BZP6
Human Synonyms  AMCASE, CHIT2, TSA1902
Human Chr (Location)  1p13.2; chr1:111290852-111320566 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Chia1 interacts with 56 markers (Mir18, Mir18b, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process apoptotic process, carbohydrate metabolic process, ...
Component cytoplasm, extracellular region, ...
Function chitinase activity, chitin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (1)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(690)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(690) cDNA(690)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023684 (Evidence)
Ensembl Gene ModelENSMUSG00000062778 (Evidence)
Entrez Gene81600 (Evidence)
UniGene46418
DFCITC1573958
DoTSDT.91397031, DT.91568021
NIA Mouse Gene IndexU003703
EC3.2.1.14
Consensus CDS ProjectCCDS38585.1
International Mouse Knockout Project StatusChia1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023684 VEGA Gene Model | MGI Sequence Detail 18892 C57BL/6J ±  kb
transcript OTTMUST00000057828 VEGA | MGI Sequence Detail 1681 Not Applicable 
polypeptide OTTMUSP00000027956 VEGA | MGI Sequence Detail 473 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011583 Chitinase II
InterPro IPR002557 Chitin binding domain
InterPro IPR013781 Glycoside hydrolase, catalytic domain
InterPro IPR001579 Glycoside hydrolase, chitinase active site
InterPro IPR001223 Glycoside hydrolase, family 18, catalytic domain
InterPro IPR017853 Glycoside hydrolase, superfamily
Protein Ontology PR:000005425 acidic mammalian chitinase
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202092 Hussain M, et al., New paralogues and revised time line in the expansion of the vertebrate GH18 family. J Mol Evol. 2013 Apr;76(4):240-60
All references(37)
Other
accession IDs
MGI:1913535

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory