Chia
Gene Detail

Symbol Name ID

Chia chitinase, acidic MGI:1932052

Synonyms

2200003E03Rik, AMCase, YNL

Feature Type

protein coding gene

Genetic Map

Chromosome 3

46.49 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:106113229-106132120 bp, + strand From VEGA annotation of GRCm38   18892 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:75168  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 4 zebrafish

Protein SuperFamily: chitinase-like protein
Gene Tree: Chia

Human homologs

Human Homolog		CHIA, chitinase, acidic
NCBI Gene ID		27159
neXtProt AC		NX_Q9BZP6
Human Synonyms		AMCASE, CHIT2, TSA1902
Human Chr (Location)		1p13.2; chr1:111833474-111863188 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (26 annotations)

Process	apoptotic process, carbohydrate metabolic process, ...
Component	cytoplasm, extracellular region, ...
Function	catalytic activity, chitinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (1)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(691)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(691) cDNA(691)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000023684 (Evidence)
Ensembl Gene Model	ENSMUSG00000062778 (Evidence)
Entrez Gene	81600 (Evidence)
UniGene	46418
DFCI	TC1573958
DoTS	DT.91397031, DT.91568021
NIA Mouse Gene Index	U003703
EC	3.2.1.14
Consensus CDS Project	CCDS38585.1
International Mouse Knockout Project Status	Chia

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023684	VEGA Gene Model | MGI Sequence Detail	18892	C57BL/6J
transcript	OTTMUST00000057828	VEGA | MGI Sequence Detail	1681	Not Applicable
polypeptide	OTTMUSP00000027956	VEGA | MGI Sequence Detail	473	Not Applicable

All sequences(35) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(66 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011583	Chitinase II
InterPro	IPR002557	Chitin binding domain
InterPro	IPR013781	Glycoside hydrolase, catalytic domain
InterPro	IPR001579	Glycoside hydrolase, chitinase active site
InterPro	IPR001223	Glycoside hydrolase, family 18, catalytic domain
InterPro	IPR017853	Glycoside hydrolase, superfamily
Protein Ontology	PR:000005425	acidic mammalian chitinase

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:178114 Pei L, et al., Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nat Med. 2011;17(11):1466-72
All references(35)

Other accession IDs

MGI:1913535