Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CFHR1,CFHR2
  • Mouse genes Cfhr1
  • Rat genes Cfhr1
  • Zfish genes cfh,cfhl1,cfhl2,cfhl3,cfhl5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cfhr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CFHR2	IPI	UniProtKB:P36980	Human	PMID:23487775
Molecular Function	GO:0042802	identical protein binding	CFHR2	IPI	UniProtKB:P36980	Human	PMID:23728178
Molecular Function	GO:0042802	identical protein binding	CFHR2	IPI	UniProtKB:P36980	Human	PMID:24260121
Molecular Function	GO:0042802	identical protein binding	CFHR1	IPI	UniProtKB:Q03591	Human	PMID:19528535
Molecular Function	GO:0042802	identical protein binding	CFHR1	IPI	UniProtKB:Q03591	Human	PMID:23487775
Molecular Function	GO:0042802	identical protein binding	CFHR1	IPI	UniProtKB:Q03591	Human	PMID:23728178
Molecular Function	GO:0042802	identical protein binding	CFHR1	IPI	UniProtKB:Q03591	Human	PMID:31273197
Molecular Function	GO:0005515	protein binding	CFHR2	IPI	UniProtKB:Q03591	Human	PMID:23487775
Molecular Function	GO:0005515	protein binding	CFHR2	IPI	UniProtKB:Q03591	Human	PMID:23728178
Molecular Function	GO:0005515	protein binding	CFHR2	IPI	UniProtKB:Q03591	Human	PMID:31273197
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P01031	Human	PMID:19528535
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P26022:PRO_0000023545	Human	PMID:22786770
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P36980	Human	PMID:23487775
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:Q9BXR6	Human	PMID:23487775
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P36980	Human	PMID:23728178
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:Q9BXR6	Human	PMID:23728178
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P02741	Human	PMID:28533443
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P26022:PRO_0000023545	Human	PMID:28533443
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:P36980	Human	PMID:31273197
Molecular Function	GO:0005515	protein binding	CFHR1	IPI	UniProtKB:Q9UHX3	Human	PMID:31273197
Cellular Component	GO:0072562	blood microparticle	CFHR1	HDA		Human	PMID:22516433
Cellular Component	GO:0032991	protein-containing complex	CFHR2	IDA		Human	PMID:23487775
Cellular Component	GO:0032991	protein-containing complex	CFHR1	IDA		Human	PMID:23487775
Biological Process	GO:0051838	cytolysis by host of symbiont cells	CFHR2	IMP		Human	PMID:23487775
Biological Process	GO:0051838	cytolysis by host of symbiont cells	CFHR1	IMP		Human	PMID:23487775
Biological Process	GO:0032091	negative regulation of protein binding	CFHR2	IMP		Human	PMID:23487775
Biological Process	GO:0032091	negative regulation of protein binding	CFHR1	IMP		Human	PMID:23487775

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern