Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDKAL1
  • Mouse genes Cdkal1
  • Rat genes Cdkal1
  • Zfish genes cdkal1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdkal1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035598	N6-threonylcarbomyladenosine methylthiotransferase activity	Cdkal1	IMP	MGI:MGI:5301443	Mouse	PMID:21841312
Molecular Function	GO:0005515	protein binding	CDKAL1	IPI	UniProtKB:P06239	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKAL1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDKAL1	IPI	UniProtKB:P54252	Human	PMID:32814053
Cellular Component	GO:0005783	endoplasmic reticulum	Cdkal1	IDA		Mouse	PMID:21151568
Cellular Component	GO:0016020	membrane	CDKAL1	HDA		Human	PMID:19946888
Cellular Component	GO:0005791	rough endoplasmic reticulum	Cdkal1	IDA		Mouse	PMID:21841312
Biological Process	GO:0031018	endocrine pancreas development	cdkal1	IMP	ZFIN:ZDB-MRPHLNO-160621-13	Zfish	PMID:26963759
Biological Process	GO:1990145	maintenance of translational fidelity	Cdkal1	IMP	MGI:MGI:5301443	Mouse	PMID:21841312
Biological Process	GO:1990798	pancreas regeneration	cdkal1	IMP	ZFIN:ZDB-MRPHLNO-160621-13	Zfish	PMID:26963759
Biological Process	GO:0035600	tRNA methylthiolation	Cdkal1	IMP	MGI:MGI:5301443	Mouse	PMID:21841312
Biological Process	GO:0003323	type B pancreatic cell development	cdkal1	IMP	ZFIN:ZDB-MRPHLNO-160621-13	Zfish	PMID:26963759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern