Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCR4
  • Mouse genes Ccr4
  • Rat genes Ccr4
  • Zfish genes cabz01093075.1,ccr11.1,ccr2,ccr8.1,si:ch211-207g17.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccr4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016493	C-C chemokine receptor activity	Ccr4	IMP	MGI:MGI:2136258	Mouse	PMID:10811868
Molecular Function	GO:0005515	protein binding	CCR4	IPI	UniProtKB:Q92583	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCR4	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Cellular Component	GO:0009897	external side of plasma membrane	Ccr4	IDA		Mouse	PMID:19008373
Cellular Component	GO:0043025	neuronal cell body	Ccr4	IDA		Rat	PMID:11438578|RGD:2306307
Cellular Component	GO:0005886	plasma membrane	CCR4	IDA		Human	GO_REF:0000052
Biological Process	GO:0006935	chemotaxis	Ccr4	IMP	MGI:MGI:2136258	Mouse	PMID:10811868
Biological Process	GO:0048872	homeostasis of number of cells	Ccr4	IMP	MGI:MGI:2136258	Mouse	PMID:24069263
Biological Process	GO:0006954	inflammatory response	Ccr4	IMP	MGI:MGI:2136258	Mouse	PMID:10811868
Biological Process	GO:1904936	interneuron migration	Ccr4	IMP	MGI:MGI:1934407	Mouse	PMID:16262623
Biological Process	GO:0042117	monocyte activation	ccr2	IMP	ZFIN:ZDB-MRPHLNO-171025-3	Zfish	PMID:28844797
Biological Process	GO:0001764	neuron migration	Ccr4	IMP	MGI:MGI:1934407	Mouse	PMID:16262623
Biological Process	GO:0050927	positive regulation of positive chemotaxis	Ccr4	IDA		Rat	PMID:12651599|RGD:2306306
Biological Process	GO:0046677	response to antibiotic	Ccr4	IEP		Rat	PMID:15993846|RGD:2306304
Biological Process	GO:0009617	response to bacterium	Ccr4	IEP		Rat	PMID:14727120|RGD:2306305
Biological Process	GO:0009314	response to radiation	Ccr4	IEP		Rat	PMID:19084914|RGD:2306303
Biological Process	GO:0002507	tolerance induction	Ccr4	IMP	MGI:MGI:2136258	Mouse	PMID:15809349

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern