Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCNK
  • Mouse genes Ccnk
  • Rat genes Ccnk
  • Zfish genes ccnk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccnk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	CCNK	IDA		Human	PMID:9632813
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q93062	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:O14503	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:O14777	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q14004	Human	PMID:26748711
Molecular Function	GO:0005515	protein binding	CCNK	IPI	UniProtKB:Q14004	Human	PMID:32707033
Molecular Function	GO:0019901	protein kinase binding	CCNK	IPI	UniProtKB:Q14004	Human	PMID:22012619
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CCNK	IDA		Human	PMID:9632813
Cellular Component	GO:0002944	cyclin K-CDK12 complex	CCNK	IPI		Human	PMID:26597175
Cellular Component	GO:0002944	cyclin K-CDK12 complex	CCNK	IPI	UniProtKB:Q9NYV4	Human	PMID:22012619
Cellular Component	GO:0002945	cyclin K-CDK13 complex	CCNK	IPI		Human	PMID:26748711
Cellular Component	GO:0002945	cyclin K-CDK13 complex	CCNK	IPI	UniProtKB:Q14004	Human	PMID:22012619
Cellular Component	GO:0005654	nucleoplasm	CCNK	IDA		Human	GO_REF:0000052
Biological Process	GO:0007417	central nervous system development	ccnk	IMP	ZFIN:ZDB-MRPHLNO-181204-4	Zfish	PMID:30122539
Biological Process	GO:0007417	central nervous system development	ccnk	IMP	ZFIN:ZDB-MRPHLNO-181204-3	Zfish	PMID:30122539
Biological Process	GO:0006974	DNA damage response	CCNK	IMP		Human	PMID:22012619
Biological Process	GO:0001701	in utero embryonic development	Ccnk	IMP	MGI:MGI:4348808	Mouse	PMID:22012619
Biological Process	GO:0044828	negative regulation by host of viral genome replication	CCNK	IDA		Human	PMID:21555514
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Ccnk	IMP		Mouse	PMID:22547058
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CCNK	IDA		Human	PMID:26748711
Biological Process	GO:0009966	regulation of signal transduction	CCNK	IDA		Human	PMID:26748711
Biological Process	GO:0006366	transcription by RNA polymerase II	CCNK	IDA		Human	PMID:22988298

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern