Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCBE1
  • Mouse genes Ccbe1
  • Rat genes
  • Zfish genes ccbe1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccbe1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	CCBE1	IDA		Human	PMID:21778431
Molecular Function	GO:0002020	protease binding	CCBE1	IPI	UniProtKB:O15072	Human	PMID:24552833
Molecular Function	GO:0005515	protein binding	CCBE1	IPI	UniProtKB:O75558	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCBE1	IPI	UniProtKB:Q53EZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCBE1	IPI	UniProtKB:Q53G59	Human	PMID:25416956
Cellular Component	GO:0031012	extracellular matrix	CCBE1	IDA		Human	PMID:21778431
Cellular Component	GO:0005615	extracellular space	CCBE1	IDA		Human	PMID:24552833
Biological Process	GO:0048514	blood vessel morphogenesis	ccbe1	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0043542	endothelial cell migration	Ccbe1	IMP	MGI:MGI:5007046	Mouse	PMID:21778431
Biological Process	GO:0030324	lung development	Ccbe1	IMP	MGI:MGI:5495674	Mouse	PMID:24733830
Biological Process	GO:0001945	lymph vessel development	Ccbe1	IMP	MGI:MGI:5495674	Mouse	PMID:24733830
Biological Process	GO:0001945	lymph vessel development	ccbe1	IMP	ZFIN:ZDB-GENO-160919-6	Zfish	PMID:25533206
Biological Process	GO:0001946	lymphangiogenesis	CCBE1	IMP		Human	PMID:19935664
Biological Process	GO:0001946	lymphangiogenesis	Ccbe1	IMP	MGI:MGI:5007046	Mouse	PMID:21778431
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP		Zfish	PMID:19287381|ZFIN:ZDB-PUB-090319-10
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:19287381
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-GENO-090506-2	Zfish	PMID:19287381
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-GENO-140701-5	Zfish	PMID:24523457
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IGI	ZFIN:ZDB-MRPHLNO-090507-1,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IGI	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:24069224
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:27345729
Biological Process	GO:0001946	lymphangiogenesis	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:19935664
Biological Process	GO:1904977	lymphatic endothelial cell migration	Ccbe1	IMP	MGI:MGI:5007046	Mouse	PMID:21778431
Biological Process	GO:0045766	positive regulation of angiogenesis	Ccbe1	IDA		Mouse	MGI:MGI:5568630|PMID:24552833
Biological Process	GO:0010595	positive regulation of endothelial cell migration	Ccbe1	IMP	MGI:MGI:5007046	Mouse	PMID:21778431
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	Ccbe1	IDA		Mouse	MGI:MGI:5568630|PMID:24552833
Biological Process	GO:0010954	positive regulation of protein processing	CCBE1	IDA		Human	PMID:24552833
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	CCBE1	IDA		Human	PMID:24552833
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	CCBE1	IDA		Human	PMID:24552833
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Ccbe1	IMP	MGI:MGI:5495674	Mouse	PMID:24733830
Biological Process	GO:0003016	respiratory system process	Ccbe1	IMP	MGI:MGI:5495674	Mouse	PMID:24733830
Biological Process	GO:0002040	sprouting angiogenesis	ccbe1	IMP		Zfish	PMID:19287381|ZFIN:ZDB-PUB-090319-10
Biological Process	GO:0002040	sprouting angiogenesis	ccbe1	IMP	ZFIN:ZDB-GENO-090506-2	Zfish	PMID:19287381
Biological Process	GO:0002040	sprouting angiogenesis	ccbe1	IGI	ZFIN:ZDB-MRPHLNO-090507-1,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0002040	sprouting angiogenesis	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:19287381
Biological Process	GO:0002040	sprouting angiogenesis	ccbe1	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	ccbe1	IGI	ZFIN:ZDB-GENO-140902-3	Zfish	PMID:25814692
Biological Process	GO:0048845	venous blood vessel morphogenesis	ccbe1	IMP		Zfish	PMID:19287381|ZFIN:ZDB-PUB-090319-10
Biological Process	GO:0060855	venous endothelial cell migration involved in lymph vessel development	ccbe1	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0060855	venous endothelial cell migration involved in lymph vessel development	ccbe1	IMP	ZFIN:ZDB-MRPHLNO-090507-1	Zfish	PMID:24523457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern