Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAPNS1
  • Mouse genes Capns1
  • Rat genes Capns1
  • Zfish genes capns1a,capns1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Capns1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	CAPNS1	IDA		Human	PMID:17646163
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	Capns1	IMP	MGI:MGI:2179226	Mouse	PMID:10825211
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	Capns1	IDA		Rat	PMID:7982961|RGD:634695
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:P17655	Human	PMID:10639123
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:P17655	Human	PMID:18519038
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:P20936	Human	PMID:18761085
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:Q96NL8	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	CAPNS1	IPI	UniProtKB:P17655	Human	PMID:28319173
Molecular Function	GO:0005515	protein binding	Capns1	IPI	UniProtKB:Q96L46	Mouse	PMID:17646163
Molecular Function	GO:0005515	protein binding	Capns1	IPI	UniProtKB:Q07009	Rat	PMID:15476820|RGD:11041056
Molecular Function	GO:0005515	protein binding	Capns1	IPI	RGD:2267|RGD:68430	Rat	PMID:18559257|RGD:9999185
Molecular Function	GO:0005515	protein binding	Capns1	IPI	UniProtKB:Q07009	Rat	PMID:19020622|RGD:5683624
Molecular Function	GO:0005515	protein binding	Capns1	IPI	UniProtKB:Q07009	Rat	PMID:19020623|RGD:11531696
Molecular Function	GO:0044877	protein-containing complex binding	Capns1	IPI	RGD:2268	Rat	PMID:7982961|RGD:634695
Cellular Component	GO:0110158	calpain complex	CAPNS1	IPI		Human	PMID:10639123
Cellular Component	GO:0005829	cytosol	CAPNS1	IDA		Human	PMID:14559243
Cellular Component	GO:0070062	extracellular exosome	CAPNS1	HDA		Human	PMID:19199708
Cellular Component	GO:0016020	membrane	CAPNS1	IDA		Human	PMID:14559243
Biological Process	GO:0030163	protein catabolic process	Capns1	IMP		Rat	PMID:7982961|RGD:634695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern