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Gene Ontology Browser
Term Detail
GO term:calcium-dependent cysteine-type endopeptidase activity
Synonym: calpain activity
GO id:GO:0004198
Definition:Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-apeptidase activity
                                        is-apeptidase activity, acting on L-amino acid peptides
                                                is-acysteine-type peptidase activity
                                                        is-acysteine-type endopeptidase activity
                                                                is-acalcium-dependent cysteine-type endopeptidase activity [GO:0004198] (20 genes, 28 annotations)
                                                                is-acysteine-type endopeptidase activity involved in apoptotic process +
                                                                is-acysteine-type endopeptidase activity involved in plant-type hypersensitive response
                                                                is-asmall conjugating protein-specific endopeptidase activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-apeptidase activity
                                        is-apeptidase activity, acting on L-amino acid peptides
                                                is-aendopeptidase activity
                                                        is-acysteine-type endopeptidase activity
                                                                is-acalcium-dependent cysteine-type endopeptidase activity [GO:0004198] (20 genes, 28 annotations)
                                                                is-acysteine-type endopeptidase activity involved in apoptotic process +
                                                                is-acysteine-type endopeptidase activity involved in plant-type hypersensitive response
                                                                is-asmall conjugating protein-specific endopeptidase activity +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory